The Christian Science Monitor is a nonprofit news organization that publishes daily articles in electronic format as well as a weekly print edition. It was founded in 1908 as a daily newspaper by Mary Baker Eddy, the founder of the Church of Christ, Scientist; as of 2011, the print circulation was 75,052. According to the organization's website, "the Monitor's global approach is reflected in how Mary Baker Eddy described its object as'To injure no man, but to bless all mankind.' The aim is to embrace the human family, shedding light with the conviction that understanding the world's problems and possibilities moves us towards solutions." The Christian Science Monitor has won seven Pulitzer Prizes and more than a dozen Overseas Press Club awards. Despite its name, the Monitor is not a religious-themed paper, does not promote the doctrine of its patron church. However, at its founder Eddy's request, a daily religious article has appeared in every issue of the Monitor; the paper has been known for avoiding sensationalism, producing a "distinctive brand of nonhysterical journalism".
In 1997, the Washington Report on Middle East Affairs, a publication critical of United States policy in the Middle East, praised the Monitor for its objective and informative coverage of Islam and the Middle East. In 2006, Jill Carroll, a freelance reporter for the Monitor, was kidnapped in Baghdad, released safely after 82 days. Although Carroll was a freelancer, the paper worked tirelessly for her release hiring her as a staff writer shortly after her abduction to ensure that she had financial benefits, according to Bergenheim. Beginning in August 2006, the Monitor published an account of Carroll's kidnapping and subsequent release, with first-person reporting from Carroll and others involved; the paper's overall circulation has ranged from a peak of over 223,000 in 1970, to just under 56,000 shortly before the suspension of the daily print edition in 2009. In response to declining circulation and the struggle to earn a profit, the church's directors and the manager of the Christian Science Publishing Society were purportedly forced to plan cutbacks and closures, which led in 1989 to the mass protest resignations by its chief editor Kay Fanning, managing editor David Anable, associate editor David Winder, several other newsroom staff.
These developments presaged administrative moves to scale back the print newspaper in favor of expansions into radio, a magazine, shortwave broadcasting, television. Expenses, however outpaced revenues, contradicting predictions by church directors. On the brink of bankruptcy, the board was forced to close the broadcast programs in 1992. In 2017 the Monitor put up a paywall on its content; the Monitor's inception was, in part, a response by its founder Mary Baker Eddy to the journalism of her day, which relentlessly covered the sensations and scandals surrounding her new religion with varying degrees of accuracy. In addition, Joseph Pulitzer's New York World was critical of Eddy, this, along with a derogatory article in McClure's, furthered Eddy's decision to found her own media outlet. Eddy required the inclusion of "Christian Science" in the paper's name, over initial opposition by some of her advisors who thought the religious reference might repel a secular audience. Eddy saw a vital need to counteract the fear spread by media reporting: Looking over the newspapers of the day, one reflects that it is dangerous to live, so loaded with disease seems the air.
These descriptions carry fears to many minds. A periodical of our own will counteract to some extent this public nuisance. Eddy declared that the Monitor's mission should be "to injure no man, but to bless all mankind". MonitoRadio was a radio service produced by the Church of Christ, Scientist between 1984 and 1997, it featured several one-hour news broadcasts a day, as well as top of the hour news bulletins. The service was heard on public radio stations throughout the United States; the Monitor launched an international broadcast over shortwave radio, called the World Service of the Christian Science Monitor. Weekdays were news-led, but weekend schedules were dedicated to religious programming; that service ceased operations on June 28, 1997. In 1986, the Monitor started producing a current affairs television series, The Christian Science Monitor Reports, distributed via syndication to television stations across the United States. In 1988, the Christian Science Monitor Reports won a Peabody Award for a series of reports on Islamic fundamentalism.
That same year, the program was canceled and the Monitor created a daily television program, World Monitor, anchored by former NBC correspondent John Hart, shown on the Discovery Channel. In 1991, World Monitor moved to a 24-hour news and information channel; the channel launched on May 1991 with programming from its Boston TV station. The only religious programming on the channel was a five-minute Christian Science program early each morning. In 1992, after eleven months on the air, the service was shut down amid huge financial losses. Programming from the Monitor Channel was carried nationally via the WWOR EMI Service; the print edition continued to struggle for readership, and, in 2004, faced a renewed mandate from the church to earn a p
Warith Deen Mohammed known as W. Deen Mohammed, Imam W. Deen Muhammad and Imam Warith Deen, was a progressive African-American Muslim leader, philosopher, Muslim revivalist, Islamic thinker who disbanded the original Nation of Islam in 1976 and transformed it into a semi orthodox mainstream Islamic movement, the World Community of Al-Islam in the West which became the American Society of Muslims, he was a son of Elijah Muhammad, the leader of the Nation of Islam from 1933 to 1975. He became the national leader of the Nation of Islam in 1975 after his father's death; as a result of his personal studies and thinking, he had led the vast majority of the members of the original NOI to mainstream, traditional Sunni Islam by 1978. With this merger, he oversaw the largest mass conversion to Islam in the history of the United States, he rejected the previous deification of Wallace Fard Muhammad, accepted whites as fellow-worshippers, forged closer ties with mainstream Muslim communities, introduced the Five Pillars of Islam into his group's theology.
Splinter groups resisting these changes formed after Elijah Muhammad's death under Louis Farrakhan, who in 1981 would revive the name Nation of Islam for his organization. Farrakhan's NOI and the previous Final Call claim direct continuity from the pre-1976 NOI. Mohammed was born Wallace Delaney Muhammad on Yemans Street in Hamtramck, Michigan in 1933. In 1980 he changed his name to Warithuddin Muhammad, Warith Deen Muhammad, which translates to'Inheritor of the Religion of Muhammad', his parents were Clara and Elijah Muhammad, both active in the Nation of Islam, the organization that preached a form of Black nationalism and its own version of Islam. From 1934 until his death in 1975, Elijah Muhammad led the Nation. Named to honor Wallace Fard Muhammad, the founder of the Nation of Islam, Mohammed grew up in Chicago, one of seven siblings, his early education came from the Muhammad University of Islam school system now known as the Clara Muhammad Schools, or Muhammad Schools. He studied Arabic as a youth under Professor Jamal Diab, a Palestinian, hired by his father to teach at the M.
U. I. in Chicago. Mohammed became a minister under his father in late 1958 and served in Philadelphia during the late 1950s and early 1960s. In 1961, on his 28th birthday, Mohammed began a term in federal prison for having refused induction into the United States military, he could have performed community service. He spent most of that time studying the main Islamic holy book, he became convinced. In 1963 he was released from prison. Close to Malcolm X, questioning the NOI, he found that by this time his viewpoints deviated from those of his father, whom he no longer believed to be a prophet; because of this conclusion, he was excommunicated five times, but by 1974, he was returned permanently to NOI. Upon the death of his father on February 25, 1975, Mohammed was unanimously chosen as the leader of the Nation of Islam and introduced to the NOI membership as such at the annual Saviours' Day convention on February 26, 1975. Among the first changes Mohammed instituted, he dropped the title Supreme Minister and took the title Chief Imam, or Imam, in 1976.
The same year, he unveiled a new flag for the NOI community. These were just two of the many reforms Mohammed introduced. Among others, he eliminated the NOI dress code, disbanded the military branch of the NOI, clarified the concept of the devil, through his Muhammad Speaks newspaper and public speeches and explained Islam's Five Pillars, he stated that his father was not a prophet. All of the over 400 temples were converted into traditional Islamic mosques, he renamed the community several times before settling on the American Society of Muslims to reflect the new thinking. Mohammed was frank about his intentions to evolve the movement. On November 19, 1978 he spoke on the "Evolution of the Nation of Islam" at the American Academy of Religion in New Orleans. Mohammed's changes reached deep into the philosophy of the movement, he rejected literal interpretations of his father's theology and Black-separatist views and on the basis of his intensive independent study of Islamic law and theology, he accepted whites as fellow worshipers.
However, he encouraged African Americans to separate themselves from their pasts, in 1976 calling upon them to change their surnames which were given to their ancestors by slave masters. He forged closer ties with mainstream Muslim communities, including Latinos, he decentralized power. On September 10, 1978 in an address in Atlanta he resigned as Chief Imam and appointed a six-member council to lead the Community. Mohammed felt quite keenly his role in reform. In an interview published in the Muhammad Speaks newspaper and conducted by his brother Jabir Herbert Muhammad, Mohammed described his role as successor to their father as that of a Mujeddid, one who would watch over the new Islam or community. In 1979 he used the title Mujeddid on his byline in his weekly articles for the Bilalian News. Warith Deen Mohammed gained widespread support among the international Muslim community, but his changes to the Nation of Islam were not universally accepted. A number of dissident groups resisted, most notably those who followed Louis Farrakhan in breaking ranks with Mohammed.
This group revived the name'Nation of Islam' in 1977. In 1995 Mohammed released a statement expressing concern about Farrakhan's motiva
Dublin University Ladies Boat Club is a Competitive rowing sports club in Dublin, Ireland. It is the Ladies' Rowing club of Trinity College Dublin informally called "Trinity Ladies" rowing club; the club colours are black and pink with white'TRINITY' lettering and a shield bearing the arms of Trinity College. DULBC is the sister club of Dublin University Boat Club. DULBC share DUBC's Islandbridge Boathouse. Many experienced joiners have learned their trade at local clubs such as Neptune; the Ladies Boat Club uses the Trinity Boat House for training. This Boat House dates back to the beginning of the 20th century and is located just inside the surrounds of War Memorial Park at Islandbridge. In 1930, a group of undergraduate female rowers in Trinity requested permission to set up a rowing club. A supportive TCD news editorial at the time stated that rowing was an excellent sport and in every way suited to woman's physique, they were unsuccessful and many joined outside clubs instead. A TCD women's rowing team did not appear until the 1960s.
But it wasn't until 1975 that a formal decision was taken to "allow" women to row competitively for Trinity. David Sanfey was Captain of DUBC at the time and in 1976, the Dublin University Ladies Boat Club was formally established; the club's formation was driven by Jane Williams. The seventies and early eighties was an era when there was still some resistance to women's rowing within established clubs; the first'Colours Rowing Challenge' between UCD Women's Boat Club and DULBC took place in 1980. The so-called Corcoran Cup has taken place every year since. By 1979, the club was competing internationally in coxed fours. Several members of the club have represented Ireland at the top level by competing in the World Championships including Nicole Ryan, Christine Caffey, Debbie Stack, Ailis Holohan and Ruth Doyle. Others, such as Kate McCullough, Luise Ronayne, Nicola Fitz-Simon, Nessa Ronayne and Claire Magee, have competed for Ireland at the Homes International Regatta and the Coupe de la Jeunesse.
Trinity Ladies won the inaugural race of the Corcoran Cup 1980. By 2014, DULBC had won the Corcoran Cup 13 times. Dublin University Ladies Boat Club
Integrin α4β1 is an integrin dimer. It is composed of CD49d and CD29; the alpha 4 subunit is 155 kDa, the beta 1 subunit is 150 kDa. The integrin VLA-4 is expressed on the cell surfaces of stem cells, progenitor cells, T and B cells, natural killer cells and neutrophils, it functions to promote an inflammatory response by the immune system by assisting in the movement of leukocytes to tissue that requires inflammation. It is a key player in cell adhesion. However, VLA-4 does not adhere to its appropriate ligands until the leukocytes are activated by chemotactic agents or other stimuli. VLA-4's primary ligands include fibronectin. One activating chemokine is SDF-1. Following SDF-1 binding, the integrin undergoes a conformational change of the alpha and beta domains, necessary to confer high binding affinity for the endothelial adhesion molecules; this change is achieved by talin or kindlin interacting with the parts of VLA-4 on the inside of the cell's surface. The expression of VLA-4 in the plasma membrane is regulated by different growth factors or chemokines depending on the cell type.
In T cells, IL-4 down-regulates the expression of VLA-4. In CD34 positive cells, IL-3 and SCF cause up-regulation, G-CSF causes down-regulation. VLA-4 can be found on hematopoietic progenitor cells; these cells are found in the bone marrow, as, where they are produced, throughout the rest of the body. VLA-4 the alpha subunit, is crucial for the localization and circulation of progenitor cells. In mice, it has been shown that injected anti-alpha antibodies result in an increase in progenitor cell circulation and duration. In order for stem cells to move into the peripheral blood stream, VLA-4 must be down-regulated on the cell surface of PBSCs. There is possibility for stem cell therapy through stimulation the conformational change; this is being studied in the field. When the alpha unit was knocked out in mice, it resulted in an embryonic lethal mutation. In multiple sclerosis, the VLA-4 integrin is essential in the processes by which T-cells gain access to the brain, it allows the cells to penetrate the blood brain barrier that restricts immune cell access.
It has been found that the severity of MS is positively correlated with the expression of alpha 4. One approach to prevent an autoimmune reaction has been to block the action of VLA-4 so that self-reactive T-cells are unable to enter the brain and thus unable to attack myelin protein, it has been found that in mice, anti-alpha 4 integrin antibodies resulted in an increase of circulating stem cell and progenitor cells. Though this failed in initial multiple sclerosis research, it is still being investigated. VLA-4 antagonists have shown potential for the treatment of several inflammatory disorders. In addition to MS, a humanized antibody, has been considered for treating asthma. There was some success in the initial human trials in treating Crohn's disease-- over 40% remission was witnessed. However, the usage of Natalizumab, an antagonist of VLA-4 integrin, remains controversial due to several side effects including Progressive multifocal leukoencephalopathy. Other allosteric antagonists have been identified.
Additionally, it has been shown that VLA-4-ligand interactions can affect the sensitivity to chemotherapy in patients with malignancies in blood-forming tissue. Integrin+alpha4beta1 at the US National Library of Medicine Medical Subject Headings ITGA4 ITGB1 Info with links in the Cell Migration Gateway
The 1964 Hounslow Council election took place on 7 May 1964 to elect members of Hounslow London Borough Council in London, England. The whole council was up for the Labour party gained control of the council; these elections were the first to the newly formed borough. Elections had taken place in the Municipal Borough of Brentford and Chiswick, Municipal Borough of Heston and Isleworth and Feltham Urban District; these boroughs and districts were joined to form the new London Borough of Hounslow by the London Government Act 1963. A total of 169 candidates stood in the election for the 60 seats being contested across 20 wards; these included a full slate from the Conservative and Labour parties, while the Liberals stood 45 candidates. Other candidates included 4 from the Communist party. All wards were three-seat wards; this election had aldermen as well as directly elected councillors. Labour got all 10 aldermen; the Council was elected in 1964 as a "shadow authority" but did not start operations until 1 April 1965.
The results saw Labour gain the new council with a majority of 36 after winning 48 of the 60 seats. Overall turnout in the election was 46.7%. This turnout included 1,011 postal votes
Mellow is an album by saxophonist Houston Person, recorded in 2009 and released on the HighNote label. In his review on Allmusic, Michael G. Nastos states "Not all mellow, Houston Person's tribute to the softer side of jazz has its moments based on the laid-back timbre of his soul rather than a program consisting of only ballads; the tenor sax he wields reflects the tradition established by Ben Webster in its soul-drenched tone, but is not as vocally pronounced or vibrato-driven.... That's not to say this marvelous tenor saxophonist has depreciated his talent as an adept technician, but at this point in his career he prefers this music on the mellow side, has no problem staying interested in that mood, no matter the tempo". On All About Jazz, Andrew Velez noted "Houston Person's Mellow could have been called "Up Close and Personal." With dozens and dozens of recordings to his credit, it's just the latest in a long list of exemplary sets that always evidence the warmth of his tone and the directness of his tenor sax phrasing.
Mixed in as well is a funky R&B feeling". "Sunny" – 5:44 "Too Late Now" – 6:27 "In a Mellow Tone" – 4:56 "To Each His Own" – 4:56 "What a Difference a Day Made" – 6:10 "Two Different Worlds" – 4:16 "Blues in the AM" – 6:42 "Who Can I Turn To?" – 5:34 "God Bless the Child" – 7:42 "Lester Leaps In" – 3:13 Houston Person – tenor saxophone John Di Martino – piano James Chirillo – guitar Ray Drummond – bass Lewis Nash – drums