The Durante-Moore Show was an old-time radio show that ran on NBC with episodes running from March 25, 1943–October 28, 1943 and on CBS with episodes running from October 8, 1943–June 27, 1947.

James Francis Durante was an American comedian, actor, singer, and pianist. His distinctive gravelly speech, Lower East Side accent, comic language-butchery, jazz-influenced songs, and prominent nose helped make him one of the United States' most familiar and popular personalities of the 1920s through the 1970s. He often referred to his nose as the schnozzola, and the word became his nickname.