The Giant Spider Invasion is a 1975 science fiction action horror film produced, composed and directed by Bill Rebane, and follows giant spiders that terrorize the town of Merrill, Wisconsin and its surrounding area. The film was theatrically released in 1975 by Group 1 Films and enjoyed a considerable run to become one of the 50 top-grossing films of that year.

Bill Rebane is an American film director, producer, and screenwriter. He is best known for low budget movies such as Monster a Go-Go and The Giant Spider Invasion. Rebane also ran for Governor of Wisconsin in 1979 and 2002 as the American Reform Party candidate.