The Holston is a condominium high-rise located at 531 South Gay Street in Knoxville, Tennessee. Completed in 1913 as the headquarters for the Holston National Bank, the 14-story building was the tallest in Knoxville until the construction in the late 1920s of the Andrew Johnson Hotel, located a few blocks away. The Holston was designed by architect John Kevan Peebles and today represents the city's only Neoclassical Revival-style high rise. In 1979, the building was added to the National Register of Historic Places for its architecture and its prominent position in the Knoxville skyline.

The Andrew Johnson Building is a high-rise building in downtown Knoxville, Tennessee. Completed in 1929 as the Andrew Johnson Hotel, at 203-foot (62 m), it was Knoxville's tallest building for nearly half a century. In the 1980s, it was converted to office space by Knox County. In 1980, the Andrew Johnson Building was added to the National Register of Historic Places. In 2017, BNA Associates announced plans to convert it back to a hotel. The plans were approved in 2020. As of 2022, the county offices have been almost entirely vacated in preparation for the extensive renovations.