The Last Man on Earth is a 1964 post-apocalyptic science fiction horror film based on the 1954 novel I Am Legend by Richard Matheson. The film was produced by Robert L. Lippert and directed by Ubaldo Ragona and Sidney Salkow, and stars Vincent Price and Franca Bettoia. The screenplay was written in part by Matheson, but he was dissatisfied with the result and chose to be credited as "Logan Swanson". William Leicester, Furio M. Monetti, and Ubaldo Ragona finished the script.

The Omega Man is a 1971 American post-apocalyptic action film directed by Boris Sagal and starring Charlton Heston as a survivor of a pandemic. It was written by John William Corrington and Joyce Corrington, based on the 1954 novel I Am Legend by Richard Matheson. The film's producer, Walter Seltzer, went on to work with Heston again in the dystopian science-fiction film Soylent Green in 1973.