The Scalpel is a commercial skyscraper in London, United Kingdom. It is located at 52 Lime Street, on its corner with Leadenhall Street, in the City of London financial area. It is opposite the Lloyd's building and adjacent to the Willis Building. Completed in 2018, it is 190 m (620 ft) tall, with 38 storeys, and was designed by Kohn Pedersen Fox.

Leadenhall Street is a street in the City of London. It is about 1⁄3-mile-long (0.54 km) and links Cornhill in the west to Aldgate in the east. It was formerly the start of the A11 road from London to Norwich, but that route now starts further east at Aldgate.