"The Serpent's Egg" is the fifth episode of the first season of the American science fiction series Defiance, and the series' fifth episode overall. It was aired on May 13, 2013. The episode was written by David Weddle & Bradley Thompson and it was directed by Omar Madha.

The first season of the American science fiction television series Defiance premiered on Syfy on Monday April 15, 2013 and ended on July 8, 2013 with a total of 12 episodes. The show stars Grant Bowler, Julie Benz, Stephanie Leonidas, Tony Curran, Jaime Murray, Graham Greene and Mia Kirschner.