Theotokos is a title of Mary, mother of Jesus, used especially in Eastern Christianity. The usual Latin translations are Dei Genitrix or Deipara. Familiar English translations are "Mother of God" or "God-bearer" – but these both have different literal equivalents in Greek, Μήτηρ Θεοῦ and Θεοφόρος.

In Christian theology, the doctrine of incarnation teaches that the pre-existent divine person of Jesus Christ, God the Son, the second person of the Trinity, and the eternally begotten Logos, took upon human nature and "was made flesh" by being conceived in the womb of a woman, the Virgin Mary, also known as the Theotokos. The doctrine of the incarnation then entails that Jesus was at the same time both fully God and fully human.