Thermae Romae is a Japanese manga series by Mari Yamazaki. It won the third Manga Taishō and the Short Story Award at the 14th Tezuka Osamu Cultural Prize. The manga has been licensed in North America by Yen Press. Fuji TV produced a live-action film adaptation and released on April 28, 2012. A second film, Thermae Romae II, was released in 2014. An anime television adaptation by DLE Inc. aired in Japan on Fuji TV's Noitamina block in January 2012. The show has been licensed by Discotek Media in North America, and by Siren Visual in Australia.

Named after Osamu Tezuka, the Tezuka Osamu Cultural Prize is a yearly manga prize awarded to manga artists or their works that follow the Osamu Tezuka manga approach founded and sponsored by Asahi Shimbun. The prize has been awarded since 1997, in Tokyo, Japan.