Sir Thomas Browne was an English polymath and author of varied works which reveal his wide learning in diverse fields including science and medicine, religion and the esoteric. His writings display a deep curiosity towards the natural world, influenced by the Scientific Revolution of Baconian enquiry and are permeated by references to Classical and Biblical sources as well as the idiosyncrasies of his own personality. Although often described as suffused with melancholia, Browne's writings are also characterised by wit and subtle humour, while his literary style is varied, according to genre, resulting in a rich, unique prose which ranges from rough notebook observations to polished Baroque eloquence.

The Scientific Revolution was a series of events that marked the emergence of modern science during the early modern period, when developments in mathematics, physics, astronomy, biology and chemistry transformed the views of society about nature. The Scientific Revolution took place in Europe in the second half of the Renaissance period, with the 1543 Nicolaus Copernicus publication De revolutionibus orbium coelestium often cited as its beginning.