Thomas Pelham (c.1678–1759) was an English politician, a member of the Pelham family of Sussex. Returned on the family's electoral interest at Lewes in 1705, he provided a reliable Whig vote in the House of Commons, and a rather more sporadic attendance on the Board of Trade. Due to his neglect of the family electoral interest, he was nearly turned out in the 1734 election, and stood down in favor of his eldest son at the next election in 1741.

Lewes is a constituency in East Sussex represented in the House of Commons of the UK Parliament since 2015 by Maria Caulfield, a Conservative.