Three Men on a Horse is a three-act farce co-authored by John Cecil Holm and George Abbott. The comedy focuses on a man who discovers he has a talent for choosing the winning horse in a race as long as he never places a bet himself. Originally titled Hobby Horse by John Cecil Holm, Three Men On A Horse was a property controlled and produced by Alex Yokel, who reached out to Warner Bros. for financial assistance; Warners agreed to provide financing on the condition Yokel find someone to doctor the script and direct the Broadway production. George Abbott, the director, who had since 1932 directed and produced each of his Broadway productions, immediately saw the potential and rewrote the script and agreed to direct if he received co-author credit and split the author's royalties with Holm. Abbott wrote a third act, resulting in a new three-act play titled Three Men on a Horse.

Dorothy Loudon was an American actress and singer. She won the Tony Award for Best Lead Actress in a Musical in 1977 for her performance as Miss Hannigan in Annie. Loudon was also nominated for Tony Awards for her lead performances in the musicals The Fig Leaves Are Falling and Ballroom, as well as a Golden Globe award for her appearances on The Garry Moore Show.