The Thule or proto-Inuit were the ancestors of all modern Inuit. They developed in coastal Alaska by the year 1000 and expanded eastward across northern Canada, reaching Greenland by the 13th century. In the process, they replaced people of the earlier Dorset culture that had previously inhabited the region. The appellation "Thule" originates from the location of Thule in northwest Greenland, facing Canada, where the archaeological remains of the people were first found at Comer's Midden.

Qaanaaq, formerly known as Thule or New Thule, is the main town in the northern part of the Avannaata municipality in northwestern Greenland. The town has a population of 646 as of 2020. The population was forcibly relocated from its former, traditional home, which was expropriated for the construction of a United States Air Force base in 1953. The inhabitants of Qaanaaq speak the local Inuktun language and many also speak Kalaallisut and Danish.