Thyateira was the name of an ancient Greek city in Asia Minor, now the modern Turkish city of Akhisar, Manisa Province. The name is probably Lydian. It lies in the far west of Turkey, south of Istanbul and almost due east of Athens. It is about 50 miles (80 km) from the Aegean Sea.

Akhisar is a municipality and district of Manisa Province, Turkey. Its area is 1,645 km2, and its population is 177,419 (2022). It is the site of the ancient city of Thyatira.