The Tiber is the third-longest river in Italy and the longest in Central Italy, rising in the Apennine Mountains in Emilia-Romagna and flowing 406 km (252 mi) through Tuscany, Umbria, and Lazio, where it is joined by the River Aniene, to the Tyrrhenian Sea, between Ostia and Fiumicino. It drains a basin estimated at 17,375 km2 (6,709 sq mi). The river has achieved lasting fame as the main watercourse of the city of Rome, which was founded on its eastern banks.

Latin is a classical language belonging to the Italic branch of the Indo-European languages. Considered a dead language, Latin was originally spoken in Latium, the lower Tiber area around Rome. Through the expansion of the Roman Republic it became the dominant language in the Italian Peninsula and subsequently throughout the Roman Empire. Even after the fall of Western Rome, Latin remained the common language of international communication, science, scholarship and academia in Europe until well into the early 19th century, when regional vernaculars supplanted it in common academic and political usage—including its own descendants, the Romance languages. For most of the time it was used, it would be considered a dead language in the modern linguistic definition; that is, it lacked native speakers, despite being used extensively and actively.