Tioga County is a county in the Commonwealth of Pennsylvania. As of the 2020 census, the population was 41,045. Its county seat is Wellsboro. The county was created on March 26, 1804, from part of Lycoming County and later organized in 1812. It is named for the Tioga River. The county is part of the North Central Pennsylvania region of the state.

Wellsboro is a borough and county seat of Tioga County, Pennsylvania. The borough was founded by Benjamin Wistar Morris. It is located 52 miles (84 km) northwest of Williamsport. The population was 3,472 at the 2020 census.