Tissue transglutaminase
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Tissue transglutaminase is a 78-kDa, calcium-dependent enzyme of the protein-glutamine γ-glutamyltransferases family. Like other transglutaminases, it crosslinks proteins between an ε-amino group of a
Figure 1: Transamidation (crosslinking) and deamidation mechanisms of tissue transglutaminase
Figure 3: Compact (inactive) and extended (active) conformations of tTG
1kv3: HUMAN TISSUE TRANSGLUTAMINASE IN GDP BOUND FORM
Tgm 2 tm 1aWtsi
Triticeae glutens
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Gluten is the seed storage protein in mature wheat seeds. It is the sticky substance in bread wheat which allows dough to rise and retain its shape during baking. The same, or very similar, proteins a
Tissue transglutaminase
…recognized by the antibodies specific to celiac. Anti-transglutaminase antibodies result in a form of gluten sensitivity in which a cellular response to Triticeae glutens that are crosslinked to tTG are able to stimulate transglutaminase specific B-cell responses that eventually result in the production of anti-transglutaminase…
Asian dumpling
Malted barley
Beer