Tohono Chul is a botanical garden, nature preserve, and cultural museum located in Casas Adobes, a suburb of Tucson, Arizona. The words "tohono chul" translate as "desert corner" and are borrowed from the language of the Tohono O’odham, the indigenous people of southern Arizona. The mission of Tohono Chul is to connect people with the nature, art and culture of the Sonoran Desert region and to "inspir[e] wise stewardship of the natural world".

Casas Adobes is an unincorporated community and census-designated place (CDP) located in the northern metropolitan area of Tucson, Arizona. The population was 66,795 at the 2010 census. Casas Adobes is situated south and southwest of the town of Oro Valley, and west of the community of Catalina Foothills.