The Tokushima Line is a railway line in Tokushima Prefecture, Japan, owned and operated by Shikoku Railway Company. The Tokushima Line connects Sako Station in Tokushima and Tsukuda Station in Miyoshi from west to east in central Tokushima Prefecture. As the line parallels the Yoshino River, it is officially nicknamed the "Yoshino River Blue Line" (よしの川ブルーライン). In addition to linking Tokushima and Kōchi prefectures, the line's eastern half serves the city of Tokushima as a commuter line.

Tokushima Prefecture is a prefecture of Japan located on the island of Shikoku. Tokushima Prefecture has a population of 728,633 and has a geographic area of 4,146 km2. Tokushima Prefecture borders Kagawa Prefecture to the north, Ehime Prefecture to the west, and Kōchi Prefecture to the southwest.