Tokyo Medical and Dental University is a Japanese national university located in Bunkyō, Tokyo, Japan. Established in 1928, it was the first national school of dentistry in Japan. TMDU is one of top 9 Designated National University and selected as a Top Type university of Top Global University Project by the Japanese government, and offers baccalaureate and graduate degrees in medicine, dentistry, and related fields. In 2023, the QS world university rankings ranked TMDU 3rd in the world for dentistry and 136th in the world for medicine.

Bunkyō is a special ward in the Tokyo Metropolis in Japan. Situated in the middle of the ward area, Bunkyō is a residential and educational center. Beginning in the Meiji period, literati like Natsume Sōseki, as well as scholars and politicians have lived there. Bunkyō is home to the Tokyo Dome, Judo's Kōdōkan, and the University of Tokyo's Hongo Campus. Bunkyō has a sister-city relationship with Kaiserslautern in the Rhineland-Palatinate of Germany.