The House of Tolstoy, or Tolstoi, is a family of Russian gentry that acceded to the high aristocracy of the Russian Empire. The name Tolstoy is itself derived from the Russian adjective "толстый". They are the descendants of Andrey Kharitonovich Tolstoy, who moved from Chernigov to Moscow and served under Vasily II of Moscow in the 15th century. The "wild Tolstoys", as they were known in the high society of Imperial Russia, have left a lasting legacy in Russian politics, military history, literature, and fine arts.

Count Pyotr Andreyevich Tolstoy was a Russian statesman and diplomat, prominent during and after the reign of Peter the Great. He was the ancestor of all the Counts Tolstoy, including the novelist Leo Tolstoy and Alexei Tolstoy the writer. His wife was Solomonida Timofeevna Dubrovskaya born 1660 and died 1722; he had two sons with her, Ivan and Peter. Both his sons died in exile with him the year before his own death. He was, however, survived by many grandchildren: the family was recalled by the Empress Elizabeth, daughter of Peter the Great in 1760, and had all honors and land restored.