Topeka High School (THS) is a public secondary school in Topeka, Kansas, United States. It serves students in grades 9 to 12, and is one of five high schools operated by the Topeka USD 501 school district. In the 2010–2011 school year, there were 1,840 students enrolled.

Topeka is the capital city of the U.S. state of Kansas and the seat of Shawnee County. It is along the Kansas River in the central part of Shawnee County, in northeast Kansas, in the Central United States. As of the 2020 census, the population of the city was 126,587. The Topeka metropolitan statistical area, which includes Shawnee, Jackson, Jefferson, Osage, and Wabaunsee Counties, had a population of 233,870 in the 2010 census.