On April 22, 2020, an outbreak of discrete supercell thunderstorms across portions of Oklahoma, Texas, and Louisiana led to widespread severe weather, including multiple strong tornadoes. Two people were killed by a high-end EF2 that struck the town of Madill, Oklahoma, and three more were killed by an EF3 wedge tornado that moved through Onalaska, Texas. Dozens of others were injured as well. The event came to fruition as a trough progressed eastward across the United States, interacting with a moist and unstable environment. Tornado activity continued into Arkansas, Louisiana, Mississippi, Alabama, Florida, and Georgia overnight into the day on April 23. Isolated tornado activity also occurred during the overnight hours on April 21.

Madill is a city in and the county seat of Marshall County, Oklahoma, United States. It was named in honor of George Alexander Madill, an attorney for the St. Louis-San Francisco Railway. The population at the 2010 census was 3,770, an increase of 10.8 percent from 3,410 at the 2000 census. It is best known as the site of the annual National Sand Bass Festival. It is part of the Texoma region.