Tottori Prefecture is a prefecture of Japan located in the Chūgoku region of Honshu. Tottori Prefecture is the least populous prefecture of Japan at 538,525 (2023) and has a geographic area of 3,507.13 square kilometres (1,354.11 sq mi). Tottori Prefecture borders Shimane Prefecture to the west, Hiroshima Prefecture to the southwest, Okayama Prefecture to the south, and Hyōgo Prefecture to the east.

The Chūgoku region , also known as the San'in-San'yō region, is the westernmost region of Honshū, the largest island of Japan. It consists of the prefectures of Hiroshima, Okayama, Shimane, Tottori and Yamaguchi. In 2010, it had a population of 7,563,428.