The Panasonic Toughbook is a line of rugged computers produced and marketed by Panasonic. The first model, the CF-25, was introduced in 1996. The Toughbook brand mainly competes with other lines of rugged computers, such as Dell's Rugged Extreme.

A rugged computer or ruggedized computer is a computer specifically designed to operate reliably in harsh usage environments and conditions, such as strong vibrations, extreme temperatures and wet or dusty conditions. They are designed from inception for the type of rough use typified by these conditions, not just in the external housing but in the internal components and cooling arrangements as well.