Tower Grove East is a neighborhood of St. Louis, Missouri. The Tower Grove East neighborhood is bordered by Shenandoah Avenue to the north, Nebraska Avenue to the east, Gravois Avenue to the south, and south Grand Boulevard to the west.

The streets of St. Louis, Missouri, United States, and the surrounding area of Greater St. Louis are under the jurisdiction of the City of St. Louis Street Department. According to the department's Streets Division, there are 1,000 miles (1,600 km) of streets and 600 miles (970 km) of alleys within the city.