The Tower of Refuge from Shipwreck, referred to as the Tower of Refuge, is a stone-built castellated structure which was erected on St Mary's Isle in Douglas Bay, Isle of Man, in order to afford shelter to mariners wrecked on the rock. The tower was constructed through the endeavours of Sir William Hillary, who had been instrumental in several rescues of sailors stranded on the rock, and which culminated in the heroic rescue of the crew of the Saint George Steam Packet Company steamer RMS St George, when it foundered on the rock in the early hours of 20 November 1830. Sir William personally contributed a high proportion of the costs and secured a substantial number of public contributions for funding the structure.

St Mary's Isle is a partially submerged reef in Douglas Bay on the Isle of Man. Prior to 1832 the rock was the property of the Quane family until John Quane, Attorney General of the Isle of Man, presented the rock to Sir William Hillary, in his capacity as President of the Isle of Man District of the Royal National Lifeboat Institution to build the Tower of Refuge. Since then the custody of St Mary's Isle has been held by each president of the local lifeboat association.