Town Creek is a town in Lawrence County, Alabama, United States, and is included in the Decatur Metropolitan Area, as well as the Huntsville-Decatur Combined Statistical Area. It incorporated in March 1875. As of the 2010 census, the population of the town is 1100, down from 1216 in 2000. Since 1920, it has been the second largest town in Lawrence County after Moulton.

Lawrence County is a county in the northern part of the U.S. state of Alabama. As of the 2020 census, the population was 33,073. The county seat is Moulton. The county was named after James Lawrence, a captain in the United States Navy from New Jersey.