The transport infrastructure of Greater Manchester is built up of numerous transport modes and forms an integral part of the structure of Greater Manchester and North West England – the most populated region outside of South East England which had approximately 301 million annual passenger journeys using either buses, planes, trains or trams in 2014. Its position as a national city of commerce, education and cultural importance means the city has one of the largest and most thorough transport infrastructures which is heavily relied upon by its 2.8 million inhabitants in the Greater Manchester conurbation and further afield in the North West region. Public transport comes under the jurisdiction of Transport for Greater Manchester.

Between 1901 and 1949 Manchester Corporation Tramways was the municipal operator of electric tram services in Manchester, England. At its peak in 1928, the organisation carried 328 million passengers on 953 trams, via 46 routes, along 292 miles (470 km) of track.