The Treadmill with Vibration Isolation Stabilization System, commonly abbreviated as TVIS, is a treadmill for use on board the International Space Station and is designed to allow astronauts to run without vibrating delicate microgravity science experiments in adjacent labs. International Space Station treadmills, not necessarily described here, have included the original treadmill, the original TVIS, the БД-2, the Combined Operational Load-Bearing External Resistance Treadmill (COLBERT), and the Treadmill 2. Some share a name, some a design, some a function, some use different (passive) vibration-suppression systems, some it is unclear how they differ.

A treadmill is a device generally used for walking, running, or climbing while staying in the same place. Treadmills were introduced before the development of powered machines to harness the power of animals or humans to do work, often a type of mill operated by a person or animal treading the steps of a treadwheel to grind grain. In later times, treadmills were used as punishment devices for people sentenced to hard labour in prisons. The terms treadmill and treadwheel were used interchangeably for the power and punishment mechanisms.