1.
Livestock
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Livestock are domesticated animals raised in an agricultural setting to produce commodities such as food, fiber, and labor. The term is used to refer solely to those raised for food. In recent years, some organizations have also raised livestock to promote the survival of rare breeds, animal husbandry practices have varied widely across cultures and time periods. Originally, livestock were not confined by fences or enclosures, but these practices have largely shifted to intensive animal farming and these practices increase yield of the various commercial outputs, but have led to increased concerns about animal welfare and environmental impact. Livestock production continues to play an economic and cultural role in numerous rural communities. Livestock as a word was first used between 1650 and 1660, as a merger between the live and stock. Older English sources, such as the King James Version of the Bible, the word cattle is derived from Old North French catel, which meant all kinds of movable personal property, including livestock, which was differentiated from immovable real estate. In later English, sometimes smaller livestock such as chickens and pigs were referred to as small cattle, today, the modern meaning of cattle, without a modifier, usually refers to domesticated bovines, but sometimes livestock refers only to this subgroup. Legal definition United States federal legislation sometimes more narrowly defines the term to make specified agricultural commodities either eligible or ineligible for a program or activity, for example, the Livestock Mandatory Reporting Act of 1999 defines livestock only as cattle, swine, and sheep. Animal-rearing originated during the transition to settled farming communities from hunter-gatherer lifestyles. Animals are domesticated when their breeding and living conditions are controlled by humans, over time, the collective behaviour, lifecycle and physiology of livestock have changed radically. Many modern farm animals are unsuited to life in the wild, dogs were domesticated in East Asia about 15,000 years ago. Goats and sheep were domesticated around 8000 BC in Asia, swine or pigs were domesticated by 7000 BC in the Middle East and China. The earliest evidence of horse domestication dates to around 4000 BC, the term livestock is nebulous and may be defined narrowly or broadly. Broadly, livestock refers to any breed or population of animal kept by humans for a useful and this can mean domestic animals, semidomestic animals, or captive wild animals. Semidomesticated refers to animals which are only lightly domesticated or of disputed status and these populations may also be in the process of domestication. Some people may use the term livestock to refer to only used for red meat. Livestock are used by humans for a variety of purposes, many of which have an economic value, Livestock products include, Meat A useful form of dietary protein and energy, meat is the edible tissue of the animal carcass
2.
Cattle
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Cattle—colloquially cows—are the most common type of large domesticated ungulates. They are a prominent modern member of the subfamily Bovinae, are the most widespread species of the genus Bos, cattle are raised as livestock for meat, as dairy animals for milk and other dairy products, and as draft animals. Other products include leather and dung for manure or fuel, in some regions, such as parts of India, cattle have significant religious meaning. From as few as 80 progenitors domesticated in southeast Turkey about 10,500 years ago, according to an estimate from 2011, in 2009, cattle became one of the first livestock animals to have a fully mapped genome. Some consider cattle the oldest form of wealth, and cattle raiding consequently one of the earliest forms of theft. Cattle were originally identified as three species, Bos taurus, the European or taurine cattle, Bos indicus, the zebu, and the extinct Bos primigenius. The aurochs is ancestral to both zebu and taurine cattle and these have been reclassified as one species, Bos taurus, with three subspecies, Bos taurus primigenius, Bos taurus indicus, and Bos taurus taurus. Complicating the matter is the ability of cattle to interbreed with other related species. Hybrid individuals and even breeds exist, not only between taurine cattle and zebu, but also one or both of these and some other members of the genus Bos – yaks, banteng. Hybrids such as the breed can even occur between taurine cattle and either species of bison, leading some authors to consider them part of the genus Bos. However, cattle cannot successfully be hybridized with more distantly related bovines such as water buffalo or African buffalo, the aurochs originally ranged throughout Europe, North Africa, and much of Asia. In historical times, its range became restricted to Europe, breeders have attempted to recreate cattle of similar appearance to aurochs by crossing traditional types of domesticated cattle, creating the Heck cattle breed. Cattle did not originate as the term for bovine animals and it was borrowed from Anglo-Norman catel, itself from medieval Latin capitale principal sum of money, capital, itself derived in turn from Latin caput head. Cattle originally meant movable personal property, especially livestock of any kind, the word is a variant of chattel and closely related to capital in the economic sense. The term replaced earlier Old English feoh cattle, property, which today as fee. The word cow came via Anglo-Saxon cū, from Common Indo-European gʷōus = a bovine animal, compare Persian gâv, Sanskrit go-, Welsh buwch. The plural cȳ became ki or kie in Middle English, and a plural ending was often added, giving kine, kien. This is the origin of the now archaic English plural, kine, the Scots language singular is coo or cou, and the plural is kye
3.
Sheep
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The sheep is a quadrupedal, ruminant mammal typically kept as livestock. Like all ruminants, sheep are members of the order Artiodactyla, although the name sheep applies to many species in the genus Ovis, in everyday usage it almost always refers to Ovis aries. Numbering a little over one billion, domestic sheep are also the most numerous species of sheep. An adult female sheep is referred to as a ewe, a male as a ram or occasionally a tup, a castrated male as a wether. Sheep are most likely descended from the wild mouflon of Europe, one of the earliest animals to be domesticated for agricultural purposes, sheep are raised for fleece, meat and milk. A sheeps wool is the most widely used animal fiber, and is harvested by shearing. Ovine meat is called lamb when from younger animals and mutton when from older ones, Sheep continue to be important for wool and meat today, and are also occasionally raised for pelts, as dairy animals, or as model organisms for science. Sheep husbandry is practised throughout the majority of the inhabited world, in the modern era, Australia, New Zealand, the southern and central South American nations, and the British Isles are most closely associated with sheep production. Sheepraising has a lexicon of unique terms which vary considerably by region. Use of the sheep began in Middle English as a derivation of the Old English word scēap. A group of sheep is called a flock, herd or mob, many other specific terms for the various life stages of sheep exist, generally related to lambing, shearing, and age. Being a key animal in the history of farming, sheep have a deeply entrenched place in human culture, as livestock, sheep are most often associated with pastoral, Arcadian imagery. Sheep figure in many mythologies—such as the Golden Fleece—and major religions, in both ancient and modern religious ritual, sheep are used as sacrificial animals. Domestic sheep are relatively small ruminants, usually with a crimped hair called wool, domestic sheep differ from their wild relatives and ancestors in several respects, having become uniquely neotenic as a result of selective breeding by humans. A few primitive breeds of sheep retain some of the characteristics of their wild cousins, depending on breed, domestic sheep may have no horns at all, or horns in both sexes, or in males only. Most horned breeds have a pair, but a few breeds may have several. Another trait unique to domestic sheep as compared to wild ovines is their variation in color. Wild sheep are largely variations of brown hues, and variation within species is extremely limited, colors of domestic sheep range from pure white to dark chocolate brown, and even spotted or piebald
4.
Rumen
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The rumen, also known as a paunch, forms the larger part of the reticulorumen, which is the first chamber in the alimentary canal of ruminant animals. It serves as the site for microbial fermentation of ingested feed. The smaller part of the reticulorumen is the reticulum, which is continuous with the rumen. The rumen is composed of several muscular sacs, the sac, ventral sac, ventral blindsac. The lining of the wall is covered in small fingerlike projections called papillae. The reticulum is lined with ridges that form a honeycomb pattern. The ridges are approximately 0.1 -0.2 mm wide and are raised 5 mm above the reticulum wall, the hexagons in the reticulum are approximately 2–5 cm wide in cattle. These features increase the area of the reticulorumen wall, facilitating the absorption of volatile fatty acids. Despite the differences in the texture of the lining of the two parts of the reticulorumen, it represents one functional space. Digested food in the rumen is not uniform, but rather stratified into gas, liquid, and particles of different sizes, densities, and other physical characteristics. Additionally, digesta does not merely enter and exit the rumen without event, but it is subject to extensive mixing, after being swallowed, food travels down the oesophagus and is deposited in the dorsal part of the reticulum. Contractions of the reticulorumen propel and mix the recently ingested feed into the ruminal mat, the mat is a thick mass of digesta, consisting of partially degraded, long, fibrous material. Most material in the mat has been ingested, and as such, has considerable fermentable substrate remaining. Microbial fermentation proceeds rapidly in the mat, releasing many gases, some of these gases are trapped in the mat, causing the mat to be buoyant. As fermentation proceeds, fermentable substrate is exhausted, gas production decreases, digesta in the mat hence goes through a phase of increasing buoyancy followed by decreasing buoyancy. Simultaneously, the size of digesta particles–relatively large when ingested–is reduced by microbial fermentation and, later, incomplete digestion of plant material here will result in the formation of a type of bezoar called Phythobezoars. Once in the sac, digesta continues to ferment at decreased rates, further losing buoyancy. It is soon swept into the ventral reticulum by ruminal contractions, in the ventral reticulum, less dense, larger digesta particles may be propelled up into the oesophagus and mouth during contractions of the reticulum
5.
Abomasum
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The abomasum, also known as the maw, rennet-bag, or reed tripe, is the fourth and final stomach compartment in ruminants. It secretes rennet, which is used in cheese creation, the word abomasum is from New Latin and it was first used in English in 1706. It comes from Latin ab- + omasum intestine of an ox, the abomasums normal anatomical location is along ventral midline. It is a secretory stomach similar in anatomy and function as the monogastric stomach and it serves primarily in the acid hydrolysis of microbial and dietary protein, preparing these protein sources for further digestion and absorption in the small intestine. Dairy cattle on high production diets are susceptible to a number of pathologies, a gas-filled abomasum can move into an abnormal location, resulting in left-displaced abomasum or right-displaced abomasum. If the abomasum displaces to the right, it is at risk of torsion, a displaced abomasum will cause cows to present all or some of the following signs, loss of appetite, decrease rumen contractions, decrease cud chewing, and drop in milk production. While an LDA and RDA are not immediately life-threatening, veterinary care is required for surgical correction, milder cases can be corrected by rolling the cow over or forcing her to run up a steep hill. Abomasitis is a rare, but serious, disease of the abomasum whose causes are currently unknown. The abomasum is used to make the lampredotto, a dish of Florence. It is also fried and eaten with onions as part of the Korean dish Makchang gui, another dish made with the abomasum is Turkish Şırdan. Giving of the foreleg, cheeks and abomasum Methanogens in digestive tract of ruminants
6.
Hog maw
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Hog maw is the stomach of a pig. More specifically, it is the muscular wall of the stomach organ which contains no fat if cleaned properly. It can be found in food, Chinese, Pennsylvania Dutch, Mexican, Portuguese. In addition, it can be prepared in various ways including stewed, fried, baked, Hog maw is a Pennsylvania Dutch dish. In the Pennsylvania German language, it is known as Seimaage and it is made from a cleaned pigs stomach traditionally stuffed with cubed potatoes and loose pork sausage. Other ingredients include cabbage, onions, and spices and it was traditionally boiled in a large pot covered in water, not unlike Scottish haggis, but it can also be baked or broiled until browned or split, then it is drizzled with butter before serving. It is usually served hot on a platter, cut into slices and it can also be served cold as a sandwich. Often served in the winter, it was made on hog butchering days on the farms of Lancaster and Berks Counties, the stomach is purchased at one of the many traditional butchers at local farmers markets. The original recipe was most likely brought to Pennsylvania from the Palatinate area of Germany, indeed, Saumagen is reported to have been a favorite of former German Chancellor Helmut Kohl, a native of the Palatinate Region. As a soul food dish, hog maw has often been coupled with chitterlings, in the book Plantation Row Slave Cabin Cooking, The Roots of Soul Food hog maw is used in the Hog Maw Salad recipe. Hog maw is also prepared for New Years Day for prosperity along with other traditional Southern New Years Day dishes like collard greens. In Chinese cuisine, hog maw is often served fried with vegetables. It can also be braised, chilled, and sliced as part of a cold cut tray, Hog maws are a specialty in taco stands all over Mexico, mostly deep fried with the rest of the pork. In Puerto Rico, hog maws are called Cuajos, cuajitos is a popular street vendor food found around the island and is most often served with boiled green banana escabeche and morcilla. Gil Scott-Herons famous piece, The Revolution Will Not Be Televised, mentions such as General Abrams. The Joe Cuba Sextets song Bang Bang contains the refrain corn bread, hog maw, in The Offices December 6,2012 episode Dwight Christmas, Dwight Schrute serves hog maw as the main dish for the Dunder Mifflin Pennsylvania Dutch–themed Christmas party. In the 1995 movie Friday directed by F. Gary Gray and writers Ice Cube and DJ Pooh, Mr. Jones played by John Witherspoon, every time I come in the kitchen, you in the kitchen. Plantation Row Slave Cabin Cooking, The Roots of Soul Food - American Food History
7.
Food energy
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Food energy is chemical energy that animals derive from food and molecular oxygen through the process of cellular respiration. Humans and other animals need a minimum intake of energy to sustain their metabolism. Foods are composed chiefly of carbohydrates, fats, proteins, alcohol, water, vitamins, carbohydrates, fats, proteins, alcohol, and water represent virtually all the weight of food, with vitamins and minerals making up only a small percentage of the weight. Organisms derive food energy from carbohydrates, fats and proteins as well as organic acids, polyols. Some diet components that provide little or no energy, such as water, minerals, vitamins, cholesterol. Water, minerals, vitamins, and cholesterol are not broken down, fiber, a type of carbohydrate, cannot be completely digested by the human body. Ruminants can extract energy from the respiration of cellulose because of bacteria in their rumens. Using the International System of Units, researchers measure energy in joules or in its multiples, the kilojoule is most often used for food-related quantities. An older metric system unit of energy, still used in food-related contexts, is the calorie, more precisely. Within the European Union, both the kilocalorie and kilojoule appear on nutrition labels, in many countries, only one of the units is displayed, in the US and Canada labels spell out the unit as calorie or as Calorie. Fats and ethanol have the greatest amount of energy per gram,37 and 29 kJ/g. Proteins and most carbohydrates have about 17 kJ/g, carbohydrates that are not easily absorbed, such as fiber, or lactose in lactose-intolerant individuals, contribute less food energy. Polyols and organic acids contribute 10 kJ/g and 13 kJ/g respectively, the amount of water, fat, and fiber in foods determines those foods energy density. Theoretically, one could measure food energy in different ways, using the Gibbs free energy of combustion, however, the convention is to use the heat of the oxidation reaction, with the water substance produced being in the liquid phase. The American chemist Wilbur Atwater worked these corrections out in the late 19th century, based on the work of Atwater, it became common practice to calculate energy content of foods using 4 kcal/g for carbohydrates and proteins and 9 kcal/g for lipids. The system was improved by Annabel Merrill and Bernice Watt of the USDA. Many governments require food manufacturers to label the energy content of their products, in the European Union, manufacturers of packaged food must label the nutritional energy of their products in both kilocalories and kilojoules, when required. In Australia and New Zealand, the energy must be stated in kilojoules
8.
Carbohydrate
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A carbohydrate is a biological molecule consisting of carbon, hydrogen and oxygen atoms, usually with a hydrogen–oxygen atom ratio of 2,1, in other words, with the empirical formula Cmn. This formula holds true for monosaccharides, some exceptions exist, for example, deoxyribose, a sugar component of DNA, has the empirical formula C5H10O4. Carbohydrates are technically hydrates of carbon, structurally it is accurate to view them as polyhydroxy aldehydes and ketones. The term is most common in biochemistry, where it is a synonym of saccharide, a group that includes sugars, starch, the saccharides are divided into four chemical groups, monosaccharides, disaccharides, oligosaccharides, and polysaccharides. Monosaccharides and disaccharides, the smallest carbohydrates, are referred to as sugars. The word saccharide comes from the Greek word σάκχαρον, meaning sugar, while the scientific nomenclature of carbohydrates is complex, the names of the monosaccharides and disaccharides very often end in the suffix -ose. For example, grape sugar is the glucose, cane sugar is the disaccharide sucrose. Carbohydrates perform numerous roles in living organisms, polysaccharides serve for the storage of energy and as structural components. The 5-carbon monosaccharide ribose is an important component of coenzymes and the backbone of the genetic molecule known as RNA, the related deoxyribose is a component of DNA. Saccharides and their derivatives include many other important biomolecules that play key roles in the system, fertilization, preventing pathogenesis, blood clotting. In food science and in informal contexts, the term carbohydrate often means any food that is particularly rich in the complex carbohydrate starch or simple carbohydrates. Often in lists of information, such as the USDA National Nutrient Database, the term carbohydrate is used for everything other than water, protein, fat, ash. This will include chemical compounds such as acetic or lactic acid, carbohydrates are found in wide variety of foods. The important sources are cereals, potatoes, sugarcane, fruits, table sugar, bread, milk, starch and sugar are the important carbohydrates in our diet. Starch is abundant in potatoes, maize, rice and other cereals, sugar appears in our diet mainly as sucrose which is added to drinks and many prepared foods such as jam, biscuits and cakes. Glucose and fructose are found naturally in fruits and some vegetables. Glycogen is carbohydrate found in the liver and muscles, cellulose in the cell wall of all plant tissue is a carbohydrate. It is important in our diet as fibre which helps to maintain a healthy digestive system, formerly the name carbohydrate was used in chemistry for any compound with the formula Cm n
9.
Sugar
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Sugar is the generic name for sweet, soluble carbohydrates, many of which are used in food. There are various types of derived from different sources. Simple sugars are called monosaccharides and include glucose, fructose, the table sugar or granulated sugar most customarily used as food is sucrose, a disaccharide of glucose and fructose. Sugar is used in prepared foods and it is added to some foods, in the body, sucrose is hydrolysed into the simple sugars fructose and glucose. Other disaccharides include maltose from malted grain, and lactose from milk, longer chains of sugars are called oligosaccharides or polysaccharides. Some other chemical substances, such as glycerol may also have a sweet taste, low-calorie food substitutes for sugar, described as artificial sweeteners, include aspartame and sucralose, a chlorinated derivative of sucrose. Sugars are found in the tissues of most plants and are present in sufficient concentrations for efficient commercial extraction in sugarcane, the world production of sugar in 2011 was about 168 million tonnes. The average person consumes about 24 kilograms of sugar each year, equivalent to over 260 food calories per person, since the latter part of the twentieth century, it has been questioned whether a diet high in sugars, especially refined sugars, is good for human health. Sugar has been linked to obesity, and suspected of, or fully implicated as a cause in the occurrence of diabetes, cardiovascular disease, dementia, macular degeneration, the etymology reflects the spread of the commodity. The English word sugar ultimately originates from the Sanskrit शर्करा, via Arabic سكر as granular or candied sugar, the contemporary Italian word is zucchero, whereas the Spanish and Portuguese words, azúcar and açúcar, respectively, have kept a trace of the Arabic definite article. The Old French word is zuchre and the contemporary French, sucre, the earliest Greek word attested is σάκχαρις. The English word jaggery, a brown sugar made from date palm sap or sugarcane juice, has a similar etymological origin – Portuguese jagara from the Sanskrit शर्करा. Sugar has been produced in the Indian subcontinent since ancient times and it was not plentiful or cheap in early times and honey was more often used for sweetening in most parts of the world. Originally, people chewed raw sugarcane to extract its sweetness, sugarcane was a native of tropical South Asia and Southeast Asia. Different species seem to have originated from different locations with Saccharum barberi originating in India and S. edule, one of the earliest historical references to sugarcane is in Chinese manuscripts dating back to 8th century BC that state that the use of sugarcane originated in India. Sugar was found in Europe by the 1st century AD, but only as an imported medicine and it is a kind of honey found in cane, white as gum, and it crunches between the teeth. It comes in lumps the size of a hazelnut, sugar is used only for medical purposes. Sugar remained relatively unimportant until the Indians discovered methods of turning sugarcane juice into granulated crystals that were easier to store, crystallized sugar was discovered by the time of the Imperial Guptas, around the 5th century AD
10.
Lactose
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Lactose is a disaccharide sugar composed of galactose and glucose that is found in milk. Lactose makes up around 2–8% of milk, although the amount varies among species and individuals and it is extracted from sweet or sour whey. The name comes from lac, the Latin word for milk and it has a formula of C12H22O11 and the hydrate formula C12H22O11·H2O, making it an isomer of sucrose. The first crude isolation of lactose, by Italian physician Fabrizio Bartoletti, was published in 1633, in 1700, the Venetian pharmacist Lodovico Testi published a booklet of testimonials to the power of milk sugar to relieve, among other ailments, the symptoms of arthritis. In 1715, Testis procedure for making milk sugar was published by Antonio Vallisneri, lactose was identified as a sugar in 1780 by Carl Wilhelm Scheele. In 1812, Heinrich Vogel recognized that glucose was a product of hydrolyzing lactose, in 1856, Louis Pasteur crystallized the other component of lactose, galactose. By 1894, Emil Fischer had established the configurations of the component sugars, lactose was named by the French chemist Jean Baptiste André Dumas in 1843. Lactose is a derived from the condensation of galactose and glucose. Lactose is hydrolysed to glucose and galactose, isomerised in alkaline solution to lactulose, lactose monohydrate crystals have a characteristic tomahawk shape that can be observed with a light microscope. Several million tons are produced annually as a by-product of the dairy industry, whey is made up of 6. 5% solids of which 4. 8% is lactose that may be purified by crystallisation. Whey or milk plasma is the liquid remaining after milk is curdled and strained, lactose makes up about 2–8% of milk by weight. Industrially, lactose is produced from whey permeate – that is whey filtrated for all major proteins, the protein fraction is used in infant nutrition and sport nutrition while the permeate can be evaporated to 60–65% solids and crystallized while cooling. Lactose can also be precipitated from whey using ethanol, since it is insoluble in ethanol, lactose precipitates, in about 65% yield. Infant mammals nurse on their mothers to drink milk, which is rich in lactose, the intestinal villi secrete the enzyme called lactase to digest it. This enzyme cleaves the molecule into its two subunits, the simple sugars glucose and galactose, which can be absorbed. Since lactose occurs mostly in milk, in most mammals, the production of lactase gradually decreases with maturity due to a lack of continuing consumption. Many people with ancestry in Europe, West Asia, South Asia, the Sahel belt in West Africa, East Africa, in many of these areas, milk from mammals such as cattle, goats, and sheep is used as a large source of food. Hence, it was in these regions that genes for lifelong lactase production first evolved, the genes of adult lactose tolerance have evolved independently in various ethnic groups
11.
Dietary fiber
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Dietary fiber or roughage is the indigestible portion of food derived from plants. It has two components, Soluble fiber, which dissolves in water, is readily fermented in the colon into gases and physiologically active byproducts. It delays gastric emptying which in turn can cause a feeling of fullness. Insoluble fiber, which does not dissolve in water, is inert and provides bulking, or it can be prebiotic. Bulking fibers absorb water as they move through the digestive system, Dietary fibers can act by changing the nature of the contents of the gastrointestinal tract and by changing how other nutrients and chemicals are absorbed. Some types of soluble fiber absorb water to become a gelatinous, viscous substance which is fermented by bacteria in the digestive tract, some types of insoluble fiber have bulking action and are not fermented. Lignin, a major dietary insoluble fiber source, may alter the rate, other types of insoluble fiber, notably resistant starch, are fully fermented. A novel position has been adopted by the US Department of Agriculture to include functional fibers as isolated fiber sources that may be included in the diet, the term fiber is something of a misnomer, since many types of so-called dietary fiber are not actually fibrous. Food sources of fiber are often divided according to whether they provide soluble or insoluble fiber. Plant foods contain both types of fiber in varying degrees, according to the plants characteristics, a disadvantage of a diet high in fiber is the potential for significant intestinal gas production and bloating. Originally, fiber was defined to be the components of plants that resist human digestive enzymes, the definition was later changed to also include resistant starch, along with inulin and other oligosaccharides. Official definition of dietary fiber differs a little among different institutions, Dietary fibers are found in fruits, vegetables, the exact amount of fiber contained in the food can be seen in the following table of expected fiber in USDA food groups/subgroups Dietary fiber is found in plants. While all plants contain some fiber, plants with high concentrations are generally the most practical source. Fiber-rich plants can be eaten directly, or, alternatively, they can be used to make supplements and fiber-rich processed foods. The Academy of Nutrition and Dietetics, formerly the American Dietetic Association, some plants contain significant amounts of soluble and insoluble fiber. For example, plums and prunes have a thick skin covering a juicy pulp, the skin is a source of insoluble fiber, whereas soluble fiber is in the pulp. Grapes also contain an amount of fiber. The root of the plant, or glucomannan, produces results similar to fiber
12.
Fat
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Fat is one of the three main macronutrients, along with carbohydrate and protein. Fats, also known as triglycerides, are esters of three fatty acid chains and the alcohol glycerol, the terms oil, fat, and lipid are often confused. Oil normally refers to a fat with short or unsaturated fatty acid chains that is liquid at room temperature, lipid is the general term, as a lipid is not necessarily a triglyceride. Fats, like lipids, are generally hydrophobic, and are soluble in organic solvents. Fat is an important foodstuff for many forms of life, and they are a necessary part of the diet of most heterotrophs. Some fatty acids that are set free by the digestion of fats are called essential because they cannot be synthesized in the body from simpler constituents, there are two essential fatty acids in human nutrition, alpha-linolenic acid and linoleic acid. Other lipids needed by the body can be synthesized from these, fats and other lipids are broken down in the body by enzymes called lipases produced in the pancreas. Fats and oils are categorized according to the number and bonding of the atoms in the aliphatic chain. Fats that are saturated fats have no double bonds between the carbons in the chain, unsaturated fats have one or more double bonded carbons in the chain. The nomenclature is based on the end of the chain. This end is called the end or the n-end. Thus alpha-linolenic acid is called an omega-3 fatty acid because the 3rd carbon from that end is the first double bonded carbon in the counting from that end. Some oils and fats have double bonds and are therefore called polyunsaturated fats. Unsaturated fats can be divided into cis fats, which are the most common in nature, and trans fats. Unsaturated fats can be altered by reaction with hydrogen effected by a catalyst and this action, called hydrogenation, tends to break all the double bonds and makes a fully saturated fat. However, trans fats are generated during hydrogenation as contaminants created by a side reaction on the catalyst during partial hydrogenation. Saturated fats can stack themselves in a closely packed arrangement, so they can easily and are typically solid at room temperature. For example, animal fats tallow and lard are high in saturated fatty acid content and are solids, olive and linseed oils on the other hand are unsaturated and liquid
13.
Saturated fat
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A saturated fat is a type of fat in which the fatty acids all have single bonds. A fat is made of two kinds of molecules, monoglyceride and fatty acids. Fats are made of chains of carbon atoms. Some carbon atoms are linked by bonds and others are linked by double bonds. Double bonds can react with hydrogen to form single bonds and they are called saturated, because the second bond is broken up and each half of the bond is attached to a hydrogen atom. The fats of plants and fish are generally unsaturated, various fats contain different proportions of saturated and unsaturated fat. Certain vegetable products have high saturated fat content, such as coconut oil, many prepared foods are high in saturated fat content, such as pizza, dairy desserts, and sausage. The effect of saturated fat on risk of disease is controversial, many reviews recommend a diet low in saturated fat and argue it will lower risks of cardiovascular diseases, diabetes, or death. However, other reviews have rejected those arguments or advocated for examining the proportion of saturated to unsaturated fat in the diet, while nutrition labels regularly combine them, the saturated fatty acids appear in different proportions among food groups. Lauric and myristic acids are most commonly found in tropical oils, the saturated fat in meat, eggs, cacao, and nuts is primarily the triglycerides of palmitic and stearic acids. Sources of lower saturated fat but higher proportions of unsaturated fatty acids include olive oil, peanut oil, canola oil, avocados, safflower, corn, sunflower, soy, the effect of saturated fat on cardiovascular disease is controversial. Until the picture becomes clearer, experts recommend people stick to the current guidelines on fat consumption, the consumption of saturated fat is generally considered a risk factor for dyslipidemia, which in turn is a risk factor for some types of cardiovascular disease. There are strong, consistent, and graded relationships between saturated fat intake, blood levels, and the mass occurrence of cardiovascular disease. The relationships are accepted as causal, meta-analyses have found a significant relationship between saturated fat and serum cholesterol levels. High total cholesterol levels, which may be caused by many factors, are associated with a risk of cardiovascular disease. However, other indicators measuring cholesterol such as high total/HDL cholesterol ratio are more predictive than total serum cholesterol, in a study of myocardial infarction in 52 countries, the ApoB/ApoA1 ratio was the strongest predictor of CVD among all risk factors. Different saturated fatty acids have differing effects on various lipid levels, a meta-analysis published in 2003 found a significant positive relationship in both control and cohort studies between saturated fat and breast cancer. However two subsequent reviews have found weak or insignificant associations of saturated fat intake and breast cancer risk, one review found limited evidence for a positive relationship between consuming animal fat and incidence of colorectal cancer
14.
Monounsaturated fat
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In biochemistry and nutrition, monounsaturated fatty acids are fatty acids that have one double bond in the fatty acid chain with all of the remainder carbon atoms being single-bonded. By contrast, polyunsaturated fatty acids have more than one double bond, Fatty acids are long-chained molecules having an alkyl group at one end and a carboxylic acid group at the other end. Monounsaturated fatty acids are liquids at room temperature and semisolid or solid when refrigerated, common monounsaturated fatty acids are palmitoleic acid, cis-vaccenic acid and oleic acid. Palmitoleic acid has 16 carbon atoms with the first double bond occurring 7 carbon atoms away from the methyl group and it can be lengthened to the 18-carbon cis-vaccenic acid. Oleic acid has 18 carbon atoms with the first double bond occurring 9 carbon atoms away from the acid group. The illustrations below show a molecule of acid in Lewis formula. Polyunsaturated fats protect against cardiovascular disease by providing more membrane fluidity than monounsaturated fats, the large scale KANWU study found that increasing monounsaturated fat and decreasing saturated fat intake could improve insulin sensitivity, but only when the overall fat intake of the diet was low. However, some monounsaturated fatty acids may promote resistance, whereas polyunsaturated fatty acids may be protective against insulin resistance. Studies have shown that substituting dietary monounsaturated fat for saturated fat is associated with increased physical activity. More physical activity was associated with a higher-oleic acid diet than one of a palmitic acid diet, from the study, it is shown that more monounsaturated fats lead to less anger and irritability. Foods containing monounsaturated fats reduce low-density lipoprotein cholesterol, while possibly increasing high-density lipoprotein cholesterol, however, their true ability to raise HDL is still in debate. Levels of oleic along with other monounsaturated fatty acids in red cell membranes were positively associated with breast cancer risk. The saturation index of the same membranes was inversely associated with breast cancer risk, monounsaturated fats and low SI in erythrocyte membranes are predictors of postmenopausal breast cancer. Both of these depend on the activity of the enzyme delta-9 desaturase. In children, consumption of monounsaturated oils is associated with healthier serum lipid profiles, the Mediterranean Diet is one heavily influenced by monounsaturated fats. The diet in Crete is fairly high in total fat yet affords a protection from coronary heart disease. Monounsaturated fats are found in foods such as red meat, whole milk products, nuts and high fat fruits such as olives. Olive oil is about 75% monounsaturated fat, the high oleic variety sunflower oil contains as much as 85% monounsaturated fat
15.
Polyunsaturated fat
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Polyunsaturated fats are lipids in which the constituent hydrocarbon chain possesses two or more carbon–carbon double bonds. Polyunsaturated fat can be mostly in nuts, seeds, fish, algae, leafy greens. Unsaturated refers to the fact that the molecules contain less than the amount of hydrogen. These materials exist as cis or trans isomers depending on the geometry of the double bond, saturated fats have hydrocarbon chains which can be most readily aligned. The hydrocarbon chains in trans fats align more readily than those in cis fats and this means that, in general, the melting points of fats increase from cis to trans unsaturated and then to saturated. See the section on chemical structure of fats for more information, the position of the carbon-carbon double bonds in carboxylic acid chains in fats is designated by Greek letters. The carbon atom closest to the group is the alpha carbon. In fatty acids the carbon atom of the group at the end of the hydrocarbon chain is called the omega carbon because omega is the last letter of the Greek alphabet. Omega-3 fatty acids have a double bond three carbons away from the carbon, whereas omega-6 fatty acids have a double bond six carbons away from the methyl carbon. The illustration below shows the omega-6 fatty acid, linoleic acid, while it is the nutritional aspects of polyunsaturated fats that are generally of greatest interest, these materials do also have non-food applications. Drying oils, which polymerize on exposure to oxygen to form films, are polyunsaturated fats. The most common ones are linseed oil, tung oil, poppy seed oil, perilla oil and these oils are used to make paints and varnishes. In preliminary research, omega-3 fatty acids in algal oil, fish oil, fish, ongoing research indicates that omega-6 fatty acids in sunflower oil and safflower oil may also reduce the risk of cardiovascular disease. Among n-3 fatty acids, neither long-chain nor short-chain forms were associated with breast cancer risk. High levels of acid, however, the most abundant n-3 PUFA in erythrocyte membranes, were associated with a reduced risk of breast cancer. The DHA obtained through the consumption of polyunsaturated fatty acids is associated with cognitive. In addition DHA is vital for the grey matter structure of the human brain, dietary intake of polyunsaturated fatty acids has been shown in preliminary studies to decrease the risk of developing amyotrophic lateral sclerosis. The importance of the ratio of essential fatty acids as established by comparative studies shows an Omega-6
16.
Protein (nutrient)
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Proteins are essential nutrients for the human body. They are one of the blocks of body tissue. As a fuel, proteins provide as much energy density as carbohydrates,4 kcal per gram, in contrast, the most important aspect and defining characteristic of protein from a nutritional standpoint is its amino acid composition. Proteins are polymer chains made of amino acids linked together by peptide bonds, during human digestion, proteins are broken down in the stomach to smaller polypeptide chains via hydrochloric acid and protease actions. This is crucial for the synthesis of the amino acids that cannot be biosynthesized by the body. There are nine amino acids which humans must obtain from their diet in order to prevent protein-energy malnutrition. They are phenylalanine, valine, threonine, tryptophan, methionine, leucine, isoleucine, lysine, there are five dispensable amino acids which humans are able to synthesize in the body. These five are alanine, aspartic acid, asparagine, glutamic acid and these six are arginine, cysteine, glycine, glutamine, proline and tyrosine. Humans need the essential amino acids in certain ratios, some protein sources contain amino acids in a more or less complete sense. This has given rise to various ranking systems for protein sources, Dietary sources of protein include both animals and plants, meats, dairy products, fish and eggs as well as grains, legumes and nuts. Vegetarians and vegans can get enough essential amino acids by eating a variety of plant proteins and it is commonly believed that athletes should consume a higher-than-normal protein intake to maintain optimal physical performance. Protein is a nutrient needed by the body for growth. Aside from water, proteins are the most abundant kind of molecules in the body, Protein can be found in all cells of the body and is the major structural component of all cells in the body, especially muscle. This also includes body organs, hair and skin, proteins are also used in membranes, such as glycoproteins. When broken down into amino acids, they are used as precursors to acid, co-enzymes, hormones, immune response, cellular repair. Additionally, protein is needed to form blood cells, proteins are believed to increase performance in terms of athletics. Amino acids, the blocks of proteins, are used for building muscle tissue. Protein is only used as fuel when carbohydrates are low
17.
Vitamin
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A vitamin is an organic compound and a vital nutrient that an organism requires in limited amounts. For example, ascorbic acid is a vitamin for humans, supplementation is important for the treatment of certain health problems, but there is little evidence of nutritional benefit when used by otherwise healthy people. Thirteen vitamins are universally recognized at present, Vitamins are classified by their biological and chemical activity, not their structure. Thus, each vitamin refers to a number of compounds that all show the biological activity associated with a particular vitamin. Such a set of chemicals is grouped under an alphabetized vitamin generic descriptor title, such as vitamin A, which includes the compounds retinal, retinol, and four known carotenoids. Vitamers by definition are convertible to the form of the vitamin in the body. Some, such as vitamin D, have hormone-like functions as regulators of mineral metabolism, or regulators of cell and tissue growth and differentiation. The largest number of vitamins, the B complex vitamins, function as cofactors or the precursors for them. In this role, vitamins may be bound to enzymes as part of prosthetic groups, For example. They may also be less tightly bound to enzyme catalysts as coenzymes, for example, folic acid may carry methyl, formyl, and methylene groups in the cell. Although these roles in assisting enzyme-substrate reactions are vitamins best-known function, study of structural activity, function and their role in maintaining health is called vitaminology. Each vitamin is typically used in reactions, and therefore most have multiple functions. Vitamins are essential for the growth and development of a multicellular organism. Using the genetic blueprint inherited from its parents, a fetus begins to develop from the nutrients it absorbs and it requires certain vitamins and minerals to be present at certain times. These nutrients facilitate the chemical reactions that produce among other things, skin, bone, if there is serious deficiency in one or more of these nutrients, a child may develop a deficiency disease. Even minor deficiencies may cause permanent damage, for the most part, vitamins are obtained with food, but a few are obtained by other means. Humans can produce some vitamins from precursors they consume, examples include vitamin A, produced from beta carotene, and niacin, from the amino acid tryptophan. In those who are healthy, there is little evidence that supplements have any benefits with respect to cancer or heart disease
18.
Vitamin A
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Vitamin A is a group of unsaturated nutritional organic compounds that includes retinol, retinal, retinoic acid, and several provitamin A carotenoids. Vitamin A has multiple functions, it is important for growth and development, for the maintenance of the immune system and good vision. Vitamin A is needed by the retina of the eye in the form of retinal, which combines with protein opsin to form rhodopsin, Vitamin A also functions in a very different role as retinoic acid, which is an important hormone-like growth factor for epithelial and other cells. In foods of animal origin, the form of vitamin A is an ester, primarily retinyl palmitate. The retinol form functions as a form of the vitamin. All forms of vitamin A have a ring to which an isoprenoid chain is attached, called a retinyl group. Both structural features are essential for vitamin activity, the orange pigment of carrots can be represented as two connected retinyl groups, which are used in the body to contribute to vitamin A levels. Alpha-carotene and gamma-carotene also have a single group, which give them some vitamin activity. None of the other carotenes have vitamin activity, the carotenoid beta-cryptoxanthin possesses an ionone group and has vitamin activity in humans. Vitamin A can be found in two forms in foods, Retinol, the form of vitamin A absorbed when eating animal food sources, is a yellow. Since the pure form is unstable, the vitamin is found in tissues in a form of retinyl ester. It is also produced and administered as esters such as retinyl acetate or palmitate. Vitamin A deficiency is estimated to approximately one third of children under the age of five around the world. It is estimated to claim the lives of 670,000 children under five annually, approximately 250, 000–500,000 children in developing countries become blind each year owing to vitamin A deficiency, with the highest prevalence in Southeast Asia and Africa. Vitamin A deficiency is the cause of preventable childhood blindness. It also increases the risk of death from common childhood conditions such as diarrhea, UNICEF regards addressing vitamin A deficiency as critical to reducing child mortality, the fourth of the United Nations Millennium Development Goals. Vitamin A deficiency can occur as either a primary or a secondary deficiency, early weaning from breastmilk can also increase the risk of vitamin A deficiency. Vitamin A is a vitamin and depends on micellar solubilization for dispersion into the small intestine
19.
Folate
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Folic acid, another form of which is known as folate, is one of the B vitamins. The recommended daily level of folate is 400 micrograms from foods or dietary supplements. Folic acid is used to treat anemia caused by folic acid deficiency and it is also used as a supplement by women during pregnancy to prevent neural tube defects in the baby. Low levels in early pregnancy are believed to be the cause of more than half of babies born with neural tube defects, more than 50 countries use fortification of certain foods with folic acid as a measure to decrease the rate of NTDs in the population. Long term supplementation is also associated with reductions in the risk of stroke. It may be taken by mouth or by injection, there are no common side effects. It is not known whether high doses over a period of time are of concern. There are concerns that large amounts of folic acid might hide vitamin B12 deficiency, folic acid is essential for the body to make DNA, RNA, and metabolise amino acids which are required for cell division. As humans cannot make folic acid, it is required from the diet, not consuming enough folate can lead to folate deficiency. This may result in a type of anemia in which low numbers of red blood cells occur. Symptoms may include feeling tired, heart palpitations, shortness of breath, open sores on the tongue, deficiency in children may develop within a month of poor dietary intake. In adults normal total body folate is between 10, 000–30,000 micrograms with blood levels of greater than 7 nmol/L, folic acid was discovered between 1931 and 1943. It is on the World Health Organizations List of Essential Medicines, the wholesale cost of supplements in the developing world is between 0.001 and 0.005 USD per dose as of 2014. The term folic is from the Latin word folium, which means leaf, folates occur naturally in many foods especially dark green leafy vegetables and liver. Other names include vitamin B9, vitamin Bc, vitamin M, folacin, folic acid intake during pregnancy has been linked to a lessened risk of neural tube defects. Likewise, a meta-analysis of folic acid supplementation during pregnancy reported a 28% lower risk of congenital heart defects. The United States Preventive Services Task Force recommends folic acid supplementation for all able to become pregnant. Prenatal supplementation did not appear to reduce the risk of pre-term births, and there does not appear to be a correlation between maternal folic acid supplementation and an increased risk for asthma in the child
20.
Vitamin B12
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Vitamin B12, also called cobalamin, is a water-soluble vitamin that has a key role in the normal functioning of the brain and nervous system, and the formation of red blood cells. It is one of eight B vitamins and it is involved in the metabolism of every cell of the human body, especially affecting DNA synthesis, fatty acid and amino acid metabolism. No fungi, plants, or animals are capable of producing vitamin B12, only bacteria and archaea have the enzymes needed for its synthesis. Some substantial sources of B12 include animal products, fortified food products, vitamin B12 consists of a class of chemically related compounds, all of which show pharmacological activity. It contains the rare element cobalt positioned in the center of a planar tetra-pyrrole ring called a corrin ring. The vitamer is produced by bacteria as hydroxocobalamin, but conversion between different forms of the vitamin occurs in the body after consumption, because intrinsic factor is crucial for the normal absorption of B12, its lack in the presence of pernicious anemia causes a vitamin B12 deficiency. Many other subtler kinds of vitamin B12 deficiency and their biochemical effects have since been elucidated, due to impairment of vitamin B12 absorption during aging, people over age 60 are at risk of deficiency. The Food and Nutrition Board of the U. S, institute of Medicine updated Estimated Average Requirements and Recommended Dietary Allowances for vitamin B12 in 1998. The current EAR for vitamin B12 for women and men ages 14 and up is 2.0 μg/day, RDAs are higher than EARs so as to identify amounts that will cover people with higher than average requirements. RDA for pregnancy equals 2.6 μg/day, RDA for lactation equals 2.8 μg/day. For infants up to 12 months the Adequate Intake is 0. 4-0.5 μg/day. collectively the EARs, RDAs and ULs are referred to as Dietary Reference Intakes. As for safety, the IOM sets Tolerable Upper Intake Levels for vitamins, in the case of vitamin B12 there is no UL, as there is no human data for adverse effects from high doses. The European Food Safety Authority reviewed the same safety question and also reached the conclusion there was not sufficient evidence to set a UL for vitamin B12. For U. S. food and dietary supplement labeling purposes the amount in a serving is expressed as a percent of Daily Value. For vitamin B12 labeling purposes 100% of the Daily Value was 6.0 μg, a table of the pre-change adult Daily Values is provided at Reference Daily Intake. Food and supplement companies have until July 2018 to comply with the change, vitamin B12 deficiency can potentially cause severe and irreversible damage, especially to the brain and nervous system. Vitamin B12 deficiency can cause symptoms of mania and psychosis. Vitamin B12 deficiency is most commonly caused by low intakes, but can result from malabsorption, certain intestinal disorders, low presence of binding proteins
21.
Vitamin C
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Vitamin C, also known as ascorbic acid and L-ascorbic acid, is a vitamin found in food and used as a dietary supplement. As a supplement it is used to treat and prevent scurvy, evidence does not support use in the general population for the prevention of the common cold. It may be taken by mouth or by injection, large doses may cause gastrointestinal discomfort, headache, trouble sleeping, and flushing of the skin. Normal doses are safe during pregnancy, Vitamin C is an essential nutrient involved in the repair of tissue. Foods that contain vitamin C include citrus fruit, tomatoes, Vitamin C was discovered in 1912, isolated in 1928, and first made in 1933. It is on the World Health Organizations List of Essential Medicines, Vitamin C is available as a generic medication and over the counter. In 2015, the wholesale cost in the world was about 0.003 to 0.007 USD per tablet. In some countries, ascorbic acid may be added to such as breakfast cereal. A2012 Cochrane review found no effect of vitamin C supplementation on overall mortality, although rare in modern times, scurvy and its associated destabilization of collagen, connective tissue, and bone can be prevented by adequate vitamin C intake. A2014 review found that, Currently, the use of high-dose IV vitamin C cannot be recommended outside of a clinical trial, a 2013 Cochrane review found no evidence that vitamin C supplementation reduces the risk of lung cancer in healthy or high risk people. A2014 meta-analysis found that vitamin C intake might protect against lung cancer risk, a second meta-analysis found no effect on the risk of prostate cancer. Two meta-analyses evaluated the effect of vitamin C supplementation on the risk of colorectal cancer, one found a weak association between vitamin C consumption and reduced risk, and the other found no effect of supplementation. A2013 meta-analysis found no evidence that vitamin C supplementation reduces the risk of myocardial infarction, stroke, cardiovascular mortality, however, a second analysis found an inverse relationship between circulating vitamin C levels or dietary vitamin C and the risk of stroke. A meta-analysis of 44 clinical trials has shown a significant positive effect of vitamin C on endothelial function when taken at doses greater than 500 mg per day. The researchers noted that the effect of vitamin C supplementation appeared to be dependent on health status, a 2010 review found no role for vitamin C supplementation in the treatment of rheumatoid arthritis. Studies examining the effects of vitamin C intake on the risk of Alzheimers disease have reached conflicting conclusions, maintaining a healthy dietary intake is probably more important than supplementation for achieving any potential benefit. Vitamin C supplementation above the RDA has been used in trials to study a potential effect on preventing and slowing the progression of age-related cataract, however, no significant effects were found from the research. Vitamin Cs effect on the cold has been extensively researched
22.
Calcium in biology
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Calcium ions play a vital role in the physiology and biochemistry of organisms and the cell. Many enzymes require calcium ions as a cofactor, those of the blood-clotting cascade being notable examples, extracellular calcium is also important for maintaining the potential difference across excitable cell membranes, as well as proper bone formation. Calcium levels in mammals are tightly regulated, with acting as the major mineral storage site. Calcium ions, Ca2+, are released from bone into the bloodstream under controlled conditions, calcium is transported through the bloodstream as dissolved ions or bound to proteins such as serum albumin. Calcitriol, the form of vitamin D3, promotes absorption of calcium from the intestines. Calcitonin secreted from the cells of the thyroid gland also affects calcium levels by opposing parathyroid hormone, however. Calcium storages are intracellular organelles, that constantly accumulate Ca2+ ions, intracellular Ca2+ storages include mitochondria and the endoplasmic reticulum. Characteristic concentrations of calcium in model organisms are, in E. coli 3mM, 100nM, in budding yeast 2mM, in mammalian cell 10-100nM and this is evidenced by human plasma calcium, which is one of the most closely regulated physiological variables in the human body. Normal plasma levels vary between 1 and 2% over any given time, different tissues contain calcium in different concentrations. For instance, Ca2+ is the most important element of bone, in humans, the total body content of calcium is present mostly in the form of bone mineral. In this state, it is unavailable for exchange/bioavailability. The way to overcome this is through the process of bone resorption, the remainder of calcium is present within the extracellular and intracellular fluids. Within a typical cell, the concentration of ionized calcium is roughly 100 nM. The intracellular calcium level is relatively low with respect to the extracellular fluid, by an approximate magnitude of 12. This gradient is maintained through various plasma membrane calcium pumps that utilize ATP for energy, in electrically excitable cells, such as skeletal and cardiac muscles and neurons, membrane depolarization leads to a Ca2+ transient with cytosolic Ca2+ concentration reaching 400 nM and above. Mitochondria are capable of sequestering and storing some of that Ca2+ and it has been estimated that mitochondrial matrix free calcium concentration rises to the tens of micromolar levels in situ during neuronal activity. The effects of calcium on human cells are specific, meaning that different types of cells respond in different ways, however, in certain circumstances, its action may be more general. Ca2+ ions are one of the most widespread second messengers used in signal transduction, levels of intracellular calcium are regulated by transport proteins that remove it from the cell
23.
Human iron metabolism
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Human iron metabolism is the set of chemical reactions maintaining human homeostasis of iron at both the systemic and cellular level. The control of this necessary but potentially toxic metal is an important part of many aspects of human health, hematologists have been especially interested in systemic iron metabolism because iron is essential for red blood cells, where most of the human bodys iron is contained. Understanding iron metabolism is also important for understanding diseases of iron overload, such as hereditary hemochromatosis, iron is an essential bioelement for most forms of life, from bacteria to mammals. Its importance lies in its ability to mediate electron transfer, in the ferrous state, iron acts as an electron donor, while in the ferric state it acts as an acceptor. Thus, iron plays a role in the catalysis of enzymatic reactions that involve electron transfer. Proteins can contain iron as part of different cofactors, such as clusters and heme groups. Human cells require iron in order to obtain energy as ATP from a process known as cellular respiration. Iron is present in the clusters and heme groups of the electron transport chain proteins that generate a proton gradient that allows ATP synthase to synthesize ATP. Heme groups are part of hemoglobin, a found in red blood cells that serves to transport oxygen from the lungs to the tissues. Heme groups are present in myoglobin to store and diffuse oxygen in muscle cells. The human body needs iron for oxygen transport, oxygen is required for the functioning and survival of nearly all cell types. Oxygen is transported from the lungs to the rest of the bound to the heme group of hemoglobin in erythrocytes. In muscles cells, iron binds myoglobin, which regulates its release and its ability to donate and accept electrons means that it can catalyze the conversion of hydrogen peroxide into free radicals. Free radicals can cause damage to a variety of cellular structures. Iron bound to proteins or cofactors such as heme is safe, also, there are virtually no truly free iron ions in the cell, since they readily form complexes with organic molecules. However, some of the iron is bound to low-affinity complexes. Iron in such complexes can cause damage as described above, to prevent that kind of damage, all life forms that use iron bind the iron atoms to proteins. This binding allows cells to benefit from iron while also limiting its ability to do harm, in mammalian cells, intracellular labile iron concentrations are typically smaller than 1 micromolar, less than 5 percent of total cellular iron
24.
Magnesium in biology
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Magnesium is an essential element in biological systems. Magnesium occurs typically as the Mg2+ ion and it is an essential mineral nutrient for life and is present in every cell type in every organism. For example, ATP, the source of energy in cells. What is called ATP is often actually Mg-ATP, as such, magnesium plays a role in the stability of all polyphosphate compounds in the cells, including those associated with the synthesis of DNA and RNA. Over 300 enzymes require the presence of ions for their catalytic action, including all enzymes utilizing or synthesizing ATP. In plants, magnesium is necessary for synthesis of chlorophyll and photosynthesis, a balance of magnesium is vital to the well-being of all organisms. Magnesium is a relatively abundant ion in Earths crust and mantle and is highly bioavailable in the hydrosphere and this availability, in combination with a useful and very unusual chemistry, may have led to its utilization in evolution as an ion for signaling, enzyme activation, and catalysis. However, the nature of ionic magnesium has also led to a major challenge in the use of the ion in biological systems. Biological membranes are impermeable to magnesium, so transport proteins must facilitate the flow of magnesium, chlorophyll in plants converts water to oxygen as O2. Hemoglobin in vertebrate animals transports oxygen as O2 in the blood, chlorophyll is very similar to hemoglobin, except magnesium is at the center of the chlorophyll molecule and iron is at the center of the hemoglobin molecule, with other variations. This process keeps living cells on earth alive and produces levels of CO2 and O2 in our atmosphere that has changed with industrialization. Acute deficiency is rare, and is common as a drug side-effect than from low food intake per se. The most common symptom of excess oral magnesium intake is diarrhea, since the kidneys of adult humans excrete excess magnesium efficiently, oral magnesium poisoning in adults with normal renal function is very rare. Infants, which have less ability to excrete excess magnesium even when healthy, should not be given magnesium supplements, pharmaceutical preparations with magnesium are used to treat conditions including magnesium deficiency and hypomagnesemia, as well as eclampsia. Such preparations are usually in the form of sulfate or chloride when given parenterally. Magnesium is absorbed with reasonable efficiency by the body from any soluble magnesium salt, Magnesium is similarly absorbed from Epsom salts, although the sulfate in these salts adds to their laxative effect at higher doses. The Food and Nutrition Board of the U. S, institute of Medicine updated Estimated Average Requirements and Recommended Dietary Allowances for magnesium in 1997. The current EARs for magnesium for women and men ages 31 and up are 265 mg/day and 350 mg/day, the RDAs are 320 and 420 mg/day
25.
Manganese
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Manganese is a chemical element with symbol Mn and atomic number 25. It is not found as an element in nature, it is often found in minerals in combination with iron. Manganese is a metal with important industrial metal alloy uses, particularly in stainless steels, by the mid-18th century, Swedish chemist Carl Wilhelm Scheele had used pyrolusite to produce chlorine. Scheele and others were aware that pyrolusite contained a new element, johan Gottlieb Gahn was the first to isolate an impure sample of manganese metal in 1774, which he did by reducing the dioxide with carbon. Manganese phosphating is used for rust and corrosion prevention on steel, ionized manganese is used industrially as pigments of various colors, which depend on the oxidation state of the ions. The permanganates of alkali and alkaline earth metals are powerful oxidizers, Manganese dioxide is used as the cathode material in zinc-carbon and alkaline batteries. In biology, manganese ions function as cofactors for a variety of enzymes with many functions. Manganese enzymes are essential in detoxification of superoxide free radicals in organisms that must deal with elemental oxygen. Manganese also functions in the complex of photosynthetic plants. The element is a trace mineral for all known living organisms but is a neurotoxin. In larger amounts, and apparently with far greater effectiveness through inhalation, Manganese is a silvery-gray metal that resembles iron. It is hard and very brittle, difficult to fuse, Manganese metal and its common ions are paramagnetic. Manganese tarnishes slowly in air and oxidizes like iron in water containing dissolved oxygen, naturally occurring manganese is composed of one stable isotope, 55Mn. Eighteen radioisotopes have been isolated and described, the most stable being 53Mn with a half-life of 3.7 million years, 54Mn with a half-life of 312.3 days, and 52Mn with a half-life of 5.591 days. All of the radioactive isotopes have half-lives of less than three hours, and the majority of less than one minute. Manganese also has three meta states, Manganese is part of the iron group of elements, which are thought to be synthesized in large stars shortly before the supernova explosion. 53Mn decays to 53Cr with a half-life of 3.7 million years, because of its relatively short half-life, 53Mn is relatively rare, produced by cosmic rays impact on iron. Manganese isotopic contents are combined with chromium isotopic contents and have found application in isotope geology
26.
Phosphorus
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Phosphorus is a chemical element with symbol P and atomic number 15. As an element, phosphorus exists in two major forms—white phosphorus and red phosphorus—but because it is reactive, phosphorus is never found as a free element on Earth. At 0. 099%, phosphorus is the most abundant pnictogen in the Earths crust, with few exceptions, minerals containing phosphorus are in the maximally oxidised state as inorganic phosphate rocks. The glow of phosphorus itself originates from oxidation of the white phosphorus — a process now termed chemiluminescence, together with nitrogen, arsenic, antimony, and bismuth, phosphorus is classified as a pnictogen. Phosphates are a component of DNA, RNA, ATP, and the phospholipids, demonstrating the link between phosphorus and life, elemental phosphorus was first isolated from human urine, and bone ash was an important early phosphate source. Phosphate mines contain fossils, especially marine fossils, because phosphate is present in the deposits of animal remains. Low phosphate levels are an important limit to growth in aquatic systems. The vast majority of compounds produced are consumed as fertilisers. Phosphate is needed to replace the phosphorus that plants remove from the soil, other applications include the role of organophosphorus compounds in detergents, pesticides, and nerve agents. Phosphorus exists as several forms that exhibit different properties. The two most common allotropes are white phosphorus and red phosphorus, from the perspective of applications and chemical literature, the most important form of elemental phosphorus is white phosphorus, often abbreviated as WP. It is a soft and waxy solid consists of tetrahedral P4 molecules. This P4 tetrahedron is also present in liquid and gaseous phosphorus up to the temperature of 800 °C when it starts decomposing to P2 molecules, White phosphorus exists in two crystalline forms, α and β. At room temperature, the α-form is stable, which is common and it has cubic crystal structure and at 195.2 K, it transforms into β-form. These forms differ in terms of the orientations of the constituent P4 tetrahedra. White phosphorus is the least stable, the most reactive, the most volatile, the least dense, White phosphorus gradually changes to red phosphorus. This transformation is accelerated by light and heat, and samples of white phosphorus almost always some red phosphorus. For this reason, white phosphorus that is aged or otherwise impure is also called yellow phosphorus, when exposed to oxygen, white phosphorus glows in the dark with a very faint tinge of green and blue
27.
Zinc
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Zinc is a chemical element with the symbol Zn and atomic number 30. It is the first element in group 12 of the periodic table, in some respects zinc is chemically similar to magnesium, both elements exhibit only one normal oxidation state, and the Zn2+ and Mg2+ ions are of similar size. Zinc is the 24th most abundant element in Earths crust and has five stable isotopes, the most common zinc ore is sphalerite, a zinc sulfide mineral. The largest workable lodes are in Australia, Asia, and the United States, Zinc is refined by froth flotation of the ore, roasting, and final extraction using electricity. Zinc metal was not produced on a large scale until the 12th century in India and was unknown to Europe until the end of the 16th century, the mines of Rajasthan have given definite evidence of zinc production going back to the 6th century BC. To date, the oldest evidence of pure zinc comes from Zawar, in Rajasthan, alchemists burned zinc in air to form what they called philosophers wool or white snow. The element was named by the alchemist Paracelsus after the German word Zinke. German chemist Andreas Sigismund Marggraf is credited with discovering pure metallic zinc in 1746, work by Luigi Galvani and Alessandro Volta uncovered the electrochemical properties of zinc by 1800. Corrosion-resistant zinc plating of iron is the application for zinc. Other applications are in batteries, small non-structural castings. A variety of compounds are commonly used, such as zinc carbonate and zinc gluconate, zinc chloride, zinc pyrithione, zinc sulfide. Zinc is an essential mineral perceived by the public today as being of exceptional biologic and public health importance, Zinc deficiency affects about two billion people in the developing world and is associated with many diseases. In children, deficiency causes growth retardation, delayed sexual maturation, infection susceptibility, enzymes with a zinc atom in the reactive center are widespread in biochemistry, such as alcohol dehydrogenase in humans. Consumption of excess zinc can cause ataxia, lethargy and copper deficiency, Zinc is a bluish-white, lustrous, diamagnetic metal, though most common commercial grades of the metal have a dull finish.6 pm. The metal is hard and brittle at most temperatures but becomes malleable between 100 and 150 °C, above 210 °C, the metal becomes brittle again and can be pulverized by beating. Zinc is a conductor of electricity. For a metal, zinc has relatively low melting and boiling points, the melting point is the lowest of all the transition metals aside from mercury and cadmium. Many alloys contain zinc, including brass, Other metals long known to form binary alloys with zinc are aluminium, antimony, bismuth, gold, iron, lead, mercury, silver, tin, magnesium, cobalt, nickel, tellurium, and sodium
28.
Kilogram
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The kilogram or kilogramme is the base unit of mass in the International System of Units and is defined as being equal to the mass of the International Prototype of the Kilogram. The avoirdupois pound, used in both the imperial and US customary systems, is defined as exactly 0.45359237 kg, making one kilogram approximately equal to 2.2046 avoirdupois pounds. Other traditional units of weight and mass around the world are also defined in terms of the kilogram, the gram, 1/1000 of a kilogram, was provisionally defined in 1795 as the mass of one cubic centimeter of water at the melting point of ice. The final kilogram, manufactured as a prototype in 1799 and from which the IPK was derived in 1875, had an equal to the mass of 1 dm3 of water at its maximum density. The kilogram is the only SI base unit with an SI prefix as part of its name and it is also the only SI unit that is still directly defined by an artifact rather than a fundamental physical property that can be reproduced in different laboratories. Three other base units and 17 derived units in the SI system are defined relative to the kilogram, only 8 other units do not require the kilogram in their definition, temperature, time and frequency, length, and angle. At its 2011 meeting, the CGPM agreed in principle that the kilogram should be redefined in terms of the Planck constant, the decision was originally deferred until 2014, in 2014 it was deferred again until the next meeting. There are currently several different proposals for the redefinition, these are described in the Proposed Future Definitions section below, the International Prototype Kilogram is rarely used or handled. In the decree of 1795, the term gramme thus replaced gravet, the French spelling was adopted in the United Kingdom when the word was used for the first time in English in 1797, with the spelling kilogram being adopted in the United States. In the United Kingdom both spellings are used, with kilogram having become by far the more common, UK law regulating the units to be used when trading by weight or measure does not prevent the use of either spelling. In the 19th century the French word kilo, a shortening of kilogramme, was imported into the English language where it has used to mean both kilogram and kilometer. In 1935 this was adopted by the IEC as the Giorgi system, now known as MKS system. In 1948 the CGPM commissioned the CIPM to make recommendations for a practical system of units of measurement. This led to the launch of SI in 1960 and the subsequent publication of the SI Brochure, the kilogram is a unit of mass, a property which corresponds to the common perception of how heavy an object is. Mass is a property, that is, it is related to the tendency of an object at rest to remain at rest, or if in motion to remain in motion at a constant velocity. Accordingly, for astronauts in microgravity, no effort is required to hold objects off the cabin floor, they are weightless. However, since objects in microgravity still retain their mass and inertia, the ratio of the force of gravity on the two objects, measured by the scale, is equal to the ratio of their masses. On April 7,1795, the gram was decreed in France to be the weight of a volume of pure water equal to the cube of the hundredth part of the metre
29.
Tripe soups
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Tripe soup is a common dish in Balkan, Bulgarian, Greek, Turkish, and Eastern European cuisine. It is widely considered to be a hangover remedy, the Albanian language name is Paçe. The Bulgarian language name is шкембе чорба, from Turkish işkembe, the Serbian language name is Шкембић, from Turkish işkembe. The Croatian language name is Fileki, Tripice or Vampi, the Bosnian language name is Škembić. The Czech name is drštková polévka, often shortened to drštkovka, a French version is Tripes à la mode de Caen The German names for tripe soups include Kuttelsuppe, Flecksuppe, Saure Kutteln, or Saure Flecke. The Greek version is usually called patsás and sometimes skembés, from Turkish işkembe, the Hungarian name is pacalleves or simply pacal. The Italian name is trippa alla fiorentina The Polish name is flaki or flaczki, the Romanian name is ciorbă de burtă, from ciorbă sour soup < Turkish çorba + burtă tripe. However, if sour base made of fermented wheat bran called borş is used, the Slovak name is držková polievka. The South Slavic languages borrowed the name as shkembe chorba, the Turkish name işkembe çorbası comes from Persian language shikambeh stomach/tripe + shorba thick soup. Chorba is derived from a Persian term شوربا from shor and ba, in Bulgaria, a whole pork, beef or lamb tripe is boiled for few hours, chopped in small pieces, and returned to the broth. The soup is spiced with red paprika which is briefly fried. Traditionally, the soup is served with mashed garlic in vinegar, there is a variant of the soup with intestines instead of tripe. The soup was very popular with the classes until the late 1980s. Later they were replaced by fast food restaurants but the soup is still highly regarded, office workers avoid eating shkembe chorba at lunch, or eat it without adding garlic. In Croatian cuisine, its is known as Fileki, Tripice or Vampi, the Czech version is heavily spiced with paprika, onions and garlic resulting in very distinct spicy goulash-like flavour. There are a number of different German versions of this sour soup from southern parts of the country, including Bavaria, Saxony, seasonings include lard, onions, garlic, meat broth, wine vinegar, bay leaf, salt, and pepper. In the nineteenth century in parts of the German Empire that are now Poland, the tripe was cooked with long bones, celery root, parsley root, onions, and bay leaf. The tripe was then sliced, breaded and fried, and returned to the broth with some vinegar, marjoram, mustard, salt, the Greek version, called patsás, may be seasoned with red wine vinegar and garlic, or thickened with avgolemono
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Eastern European cuisine
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The cuisine of the region is strongly influenced by its climate and still varies, depending on a country. For example, Belarusian, Czech, Hungarian, Polish, Russian and Ukrainian cuisine show many similarities and these are substantial cuisines, meaty, rooty, smoky – part comfort food, part extravagance. The nutritional index of traditional dishes is generally high cholesterol, high sodium, english edition, Elena Molokhovets, Classic Russian Cooking, A Gift to Young Housewives. ISBN 978-0253212108 Institute of Nutrition of the Academy of Medical Scientists of the USSR, Москва, Пищевая промышленность, 1939-1999, in Russian. English edition, The Book of Tasty and Healthy Food, Iconic Cookbook of the Soviet Union, skyPeak Publishing LLC,2012, ISBN 978-0615691350 Кулинария. Москва, Пищевая промышленность,1980, ISBN 978-5952427839, in Russian, Russian Delight, A Cookbook of the Soviet People, London, Pan Books,1978 В. Похлёбкин, Кулинарный словарь от А до Я, Москва, Центрполиграф,2000, ISBN 5-227-00460-9 J. Gronow, S. Zhuravlev, The Establishment of Soviet Haute Cuisine. In Educated Tastes, Food, Drink, and Connoisseur Culture, university of California Press,2013, ISBN 978-0520275911 Anya Von Bremzen, John Welchman. Please to the Table, The Russian Cookbook, ISBN9780894807534 Metzger, Christine, Culinaria Germany. Irina Petrosian, David Underwood, Armenian Food, Fact, Fiction & Folklore, from the Caucasus to the Roof of the World, a culinary adventure. In Sami Zubaida & Richard Tapper, a Taste of Thyme, Culinary Cultures of the Middle East. London & New York, Tauris Parke Paperbacks, cS1 maint, Uses editors parameter Robert Strybel, Maria Strybel, Polish Heritage Cookery. ISBN9780781811248 Massimo Montanari, Il mondo in cucina, Tasting Food, Tasting Freedom, Excursions into Eating, Power, and the Past. Beacon Press,1997, ISBN0807046299 Mintalová - Zubercová, Zora, vydavateľstvo Matice slovenskej,2009, ISBN 978-80-89208-94-4 Л. Київ, Вища школа,1992, ISBN 5-11-002319-0 Українські страви, Київ, Державне видавництво технiчної лiтератури УРСР,1960 Л. The cuisine of the region is influenced by its climate and still varies. For example, Belarusian, Czech, Hungarian, Polish, Russian and Ukrainian cuisine show many similarities and these are substantial cuisines, meaty, rooty, smoky – part comfort food, part extravagance. The nutritional index of traditional dishes is generally high cholesterol, high sodium, english edition, Elena Molokhovets, Classic Russian Cooking, A Gift to Young Housewives
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Andouille
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Andouille is a smoked sausage made using pork, originating in France. It was brought to Louisiana by the French immigrants and Acadian exiles that would merge to create much of Cajun Culture. In the US the sausage is most often associated with Louisiana Cajun cuisine, where it is a smoked sausage made using pork, garlic, pepper, onions, wine. The pork used is mostly from a smoked Boston shoulder roast, once the casing is stuffed, the sausage is smoked again. Nicknamed The Andouille Capital of the World, the town of LaPlace, Louisiana, though somewhat similar, andouille is not to be confused with hot links or similar finely ground, high-fat, heavily peppered sausages. In France, particularly Brittany, the ingredients of andouille are primarily pig chitterlings, tripe, onions, wine. It is generally grey in color and has a distinctive odor, also, a similar sausage is available called andouillette, literally little andouille. Some varieties use the pigs entire gastrointestinal system, Andouille is also an insult in French, designating an imbecile, or a rascal. List of sausages List of smoked foods
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French cuisine
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French cuisine consists of the cooking traditions and practices from France. In the 14th century Guillaume Tirel, a chef known as Taillevent, wrote Le Viandier. During that time, French cuisine was influenced by Italian cuisine. Cheese and wine are a part of the cuisine. They play different roles regionally and nationally, with many variations, gastro-tourism and the Guide Michelin helped to acquaint people with the rich bourgeois and peasant cuisine of the French countryside starting in the 20th century. Gascon cuisine has also had influence over the cuisine in the southwest of France. Many dishes that were once regional have proliferated in variations across the country, knowledge of French cooking has contributed significantly to Western cuisines. Its criteria are used widely in Western cookery school boards and culinary education, in November 2010, French gastronomy was added by the UNESCO to its lists of the worlds intangible cultural heritage. In French medieval cuisine, banquets were common among the aristocracy, multiple courses would be prepared, but served in a style called service en confusion, or all at once. Food was generally eaten by hand, meats being sliced off in large pieces held between the thumb and two fingers, the sauces were highly seasoned and thick, and heavily flavored mustards were used. Meals often ended with an issue de table, which changed into the modern dessert. The ingredients of the time varied according to the seasons and the church calendar, and many items were preserved with salt, spices, honey. Late spring, summer, and autumn afforded abundance, while winter meals were more sparse, livestock were slaughtered at the beginning of winter. Beef was often salted, while pork was salted and smoked, bacon and sausages would be smoked in the chimney, while the tongue and hams were brined and dried. Cucumbers were brined as well, while greens would be packed in jars with salt, fruits, nuts and root vegetables would be boiled in honey for preservation. Whale, dolphin and porpoise were considered fish, so during Lent, artificial freshwater ponds held carp, pike, tench, bream, eel, and other fish. Poultry was kept in yards, with pigeon and squab being reserved for the elite. Game was highly prized, but very rare, and included venison, wild boar, hare, rabbit, kitchen gardens provided herbs, including some, such as tansy, rue, pennyroyal, and hyssop, which are rarely used today
