The Triple-A All-Star Game was an annual baseball game held from 1988 to 2019 between professional players from the affiliated Triple-A leagues of Minor League Baseball. These leagues were the International League (IL) and Pacific Coast League (PCL) from 1998 to 2019. Previously, the American Association competed along with the IL and PCL before it disbanded following the 1997 season. The 2020 game was cancelled along with the entire minor league season due to the COVID-19 pandemic. The 2021 game was postponed and not rescheduled after a delayed start to the season. There has been no announcement about its resumption in the future.

Triple-A has been the highest level of play in Minor League Baseball in the United States since 1946. Currently, two leagues operate at the Triple-A level, the International League (IL) and the Pacific Coast League (PCL). There are 30 teams, one per each Major League Baseball (MLB) franchise, with 20 in the IL and 10 in the PCL. Triple-A teams are generally located in smaller cities as well as larger metropolitan areas without MLB teams, such as Austin, Jacksonville, Columbus, and Indianapolis. Four Triple-A teams play in the same metro areas as their parent clubs.