The Trishuli River is one of the major tributaries of the Narayani River basin in central Nepal. The river is formed by the merger of the Kyirong Tsangpo and the Lende Khola originating in Gyirong County of Tibet, which join together near the Rasuwa Gadhi on the Nepal–Tibet border. The valley of the river used to be the traditional trade route between the Kathmandu Valley and Tibet.

The Gandaki River, also known as the Narayani and Gandak, is one of the major rivers in Nepal and a left-bank tributary of the Ganges in India. Its total catchment area is 46,300 km2 (17,900 sq mi), most of it in Nepal. In the Nepal Himalayas, the Gandaki is notable for its deep canyon. The basin also contains three mountains over 8,000 m (26,000 ft), namely Dhaulagiri, Manaslu and Annapurna Massif. Dhaulagiri is the highest point of the Gandaki basin.