Trouble is a five-issue romance comic book limited series published in 2003 by Marvel Comics as a part of its Epic Comics imprint. Written by Mark Millar and illustrated by Terry and Rachel Dodson, the series deals with teen pregnancy. The basic concept was created by Bill Jemas and Joe Quesada.

Mark Millar is a Scottish comic book writer who first came to prominence with a run on the superhero series The Authority, published by DC Comics' Wildstorm imprint. Millar has written extensively for Marvel Comics, including runs on The Ultimates, which has been called "the comic book of the decade" by Time magazine and described as a major inspiration for the 2012 film The Avengers by its screenwriter Zak Penn, X-Men, Fantastic Four and Avengers for Marvel's Ultimate imprint, as well as Marvel Knights Spider-Man and Wolverine. In 2006, Millar wrote the Civil War mini-series that served as the centrepiece for the eponymous company-wide crossover storyline and later inspired the Marvel Studios film Captain America: Civil War. The "Old Man Logan" storyline, published as part of Millar's run on Wolverine, served as the inspiration for the 2017 film Logan.