Tshiuetin Rail Transportation Inc. is a rail company that owns and operates a 217-kilometre (135 mi) Canadian regional railway that stretches through the wilderness of western Labrador and northeastern Quebec. It connects Emeril, Labrador with Schefferville, Quebec, on the interprovincial boundary. The company also operates a 356-kilometre (221 mi) railway that connects Sept-Îles, Quebec to Emeril. The company is the first railway in North America owned and operated by Indigenous peoples, specifically by the Innu Nation of Matimekush-Lac John, the Naskapi Nation of Kawawachikamach, and the Innu Takuaikan Uashat Mak Mani-Utenam.

Schefferville is a town in the Canadian province of Quebec. Schefferville is in the heart of the Naskapi and Innu territory in northern Quebec, less than 2 km from the border with Labrador on the north shore of Knob Lake. It is located within the Caniapiscau Regional County Municipality and has an area of 24.76 square kilometres (9.56 sq mi). Schefferville completely surrounds the autonomous Innu community of Matimekosh, and it abuts the small community of Lac-John Reserve. Both of the latter communities are First Nations Innu reserves. Schefferville is also close to the Naskapi reserved land of Kawawachikamach.