Tufts Medical Center station is an underground Massachusetts Bay Transportation Authority (MBTA) rapid transit station in Boston, Massachusetts. It serves the MBTA subway Orange Line, as well as two Silver Line bus rapid transit routes on the surface. It is named for the Tufts Medical Center and is built under a wing of the facility that crosses over Washington Street in downtown Boston between Kneeland Street in Chinatown and the Massachusetts Turnpike. The accessible station has two side platforms for the Orange Line.

The Massachusetts Bay Transportation Authority (MBTA) operates rapid transit, light rail, and bus rapid transit services in the Boston metropolitan area, collectively referred to as the rapid transit, subway, or the T system.