Tunica County is a county located in the U.S. state of Mississippi. As of the 2020 census, the population was 9,782. Its county seat is Tunica. The county is named for the Tunica Native Americans. Most migrated to central Louisiana during the colonial period.

Tunica is a town in and the county seat of Tunica County, Mississippi, United States, near the Mississippi River. Until the early 1990s when casino gambling was introduced in the area, Tunica had been one of the most impoverished places in the United States. Despite this economic improvement, Tunica's population continues to decline from its peak in 1970.