The Tuolumne Band of Me-Wuk Indians is a federally recognized tribe of Miwok people in Tuolumne County, California. The Tuolumne Band are central Sierra Miwok people. Annually, in September, the tribe holds an acorn festival and intertribal gathering.

The Miwok are members of four linguistically related Native American groups indigenous to what is now Northern California, who traditionally spoke one of the Miwok languages in the Utian family. The word Miwok means people in the Miwok languages.