The Tuqan clan is a prominent Palestinian and Jordanian political and business family. During the Ottoman era, they dominated the political and socio-economic spheres in Nablus and extended their influence to al-Salt. During that era, they were the only household that came close to establishing centralized rule over Jabal Nablus. Over the course of the 18th and 19th centuries the Tuqan family held the title of mutasallim of Nablus longer than any other local family.

Nablus is a Palestinian city in the West Bank, located approximately 49 kilometres (30 mi) north of Jerusalem, with a population of 156,906. Located between Mount Ebal and Mount Gerizim, it is the capital of the Nablus Governorate and a commercial and cultural centre of the State of Palestine, home to An-Najah National University, one of the largest Palestinian institutions of higher learning, and the Palestine Stock Exchange. Nablus is under the administration of the Palestinian National Authority (PNA).