The Baghdad Nuclear Research Facility adjacent to the Tuwaitha "Yellow Cake Factory" or Tuwaitha Nuclear Research Center contains the remains of nuclear reactors bombed by Iran in 1980, Israel in 1981, and the United States in 1991. It was used as a storage facility for spent reactor fuel and industrial and medical wastes. The radioactive material would not be useful for a fission bomb, but could be used in a dirty bomb. Following the 2003 invasion of Iraq, the facility was heavily looted by hundreds of Iraqis, though it is unclear what was taken.

Operation Scorch Sword was an Iranian airstrike on Iraq's Tuwaitha Nuclear Research Centre in 1980. Conducted eight days after the beginning of the Iraqi invasion of Iran, it was a surprise attack against the under-construction Osirak nuclear reactor, which was located 17 kilometres to the southeast of Baghdad and was widely perceived as a major asset for the then-ongoing Iraqi nuclear program. At dawn on 30 September, four Iranian F-4 Phantom IIs completed an aerial refueling near the Iran–Iraq border before flying into Iraqi airspace, where they deliberately climbed to a high altitude in order to be detected by Iraqi radar systems, albeit on a false course. Moments later, two of them peeled off and dropped to an extremely low altitude to avoid further detection and subsequently changed course for the Iraqi nuclear facility.