Two Harbors, colloquially known as "The Isthmus", is a small unincorporated community island village on the island of Santa Catalina Island, California, United States, with a population of 298. It is the second center of population on the island, besides the city of Avalon. It is mainly a resort village. It has only one restaurant, one hotel and one general store. The village has about 150 permanent residents who live on the isthmus year-round. One notable feature was the one-room schoolhouse which closed in 2014.

Santa Catalina Island is a rocky island off the coast of Southern California in the Gulf of Santa Catalina. The island covers an area of about 75 square miles. It features a diverse and rugged landscape, including rolling hills, canyons, coastal cliffs, and sandy beaches. The island's highest peak is Mount Orizaba, rising to an elevation of 2,097 feet. The island is 22 mi long and 8 mi across at its largest width. The island is situated in the Pacific Ocean, approximately 29 mi south-southwest of Long Beach, California. Politically, Catalina Island is part of Los Angeles County in District 4. Most of the island's land is unincorporated and is thus governed by the county.