Two Prudential Plaza is a 64-story skyscraper located in the Loop area of Chicago, Illinois. At 995 feet (303 m) tall, it is the seventh-tallest building in Chicago as of 2022 and the 28th-tallest in the U.S., being only five feet from 1,000 feet, making it the closest of any building under 1,000. Built in 1990, the building was designed by the firm Loebl Schlossman & Hackl, with Stephen T. Wright as the principal in charge of design. It has received eight awards, including winning the Best Structure Award from the Structural Engineers Association of Illinois in 1995.

WUSN is a country radio station in Chicago, Illinois. Owned by Audacy, Inc. and branded as "US✶99", it is based at Two Prudential Plaza in the Loop, and transmits from atop the John Hancock Center with an HD Radio signal.