Tygh Valley is a census-designated place (CDP) and unincorporated community in Wasco County, Oregon, United States. The population was 224 at the 2000 census.

U.S. Route 197 (US 197) is a north–south United States Highway, of which all but 2.76 miles of its 69.93 miles are within the state of Oregon. The highway starts in rural Wasco County in Central Oregon at an intersection with US 97. US 197 travels north as a continuation of The Dalles-California Highway No. 4 through the cities of Maupin, Tygh Valley, and Dufur to The Dalles. Within The Dalles, the highway becomes concurrent with US 30 and intersects Interstate 84 (I-84) before it crosses over the Columbia River on The Dalles Bridge into Washington. The highway continues through the neighboring city of Dallesport in Klickitat County and terminates at a junction with State Route 14 (SR 14).