The Tyrolean Rebellion is a name given to the resistance of militiamen, peasants, craftsmen and other civilians of the County of Tyrol led by Andreas Hofer supported by his wife Anna and a strategic council consisting of Josef Speckbacher, Peter Mayr, Capuchin Father Joachim Haspinger, Major Martin Teimer and Kajetan Sveth, against new legislation and a compulsory vaccination programme concerning smallpox ordered by King Maximilian I of Bavaria, followed by the military occupation of their homeland by troops organised and financed by Napoleon I of the First French Empire and Maximilian I. The broader military context is called the War of the Fifth Coalition.

The (Princely) County of Tyrol was an estate of the Holy Roman Empire established about 1140. After 1253, it was ruled by the House of Gorizia and from 1363 by the House of Habsburg. In 1804, the County of Tyrol, unified with the secularised prince-bishoprics of Trent and Brixen, became a crown land of the Austrian Empire. From 1867, it was a Cisleithanian crown land of Austria-Hungary.