U.P. Campus is a barangay in Quezon City, Metro Manila. As its name suggests, a large part of the barangay is occupied by the main Diliman campus of the University of the Philippines (UP). UP Diliman, the university campus itself, covers seven other barangays in Quezon City, namely Krus na Ligas, San Vicente, Botocan, Culiat, Old Capitol Site, Pansol, and Vasra.

Quezon City, also known as the City of Quezon and Q.C., is the most populous city in the Philippines. According to the 2020 census, it has a population of 2,960,048 people. It was founded on October 12, 1939, and was named after Manuel L. Quezon, the second president of the Philippines.