U.S. Naval Air Station Lough Foyle was a seaplane station at Lough Foyle in Ireland, which was operated by the United States Navy (USN) and commissioned on July 1, 1918 with Commander Henry D. Cooke, USN as the commanding officer. Located near Quigley's Point in County Donegal, and approximately 6 miles (9.7 km) north of Derry in County Londonderry, the station was disestablished in early 1919.

Lough Foyle, sometimes Loch Foyle, is the estuary of the River Foyle, on the north coast of Ireland. It lies between County Londonderry in Northern Ireland and County Donegal in the Republic of Ireland. Sovereignty over the waters has been in dispute since the Partition of Ireland.