U.S. Route 136 (US 136) runs east–west across central Illinois for 225.5 miles (362.9 km). US 136 enters the state from Iowa across the Keokuk–Hamilton Bridge over the Mississippi River between Keokuk, Iowa, and Hamilton, Illinois, and exits into Indiana east of Danville. The largest population centers along the route are Macomb, Rantoul, and Danville.