U.S. Route 14 (US 14) in the state of Illinois is a major arterial that runs southeast from the Wisconsin state line north of Harvard to the north side of Chicago at US 41.

Illinois Route 50 (IL 50) is a 66.49-mile-long (107.01 km) north–south state highway in northeastern Illinois. It runs from the junction with U.S. Route 45 (US 45) and U.S. Route 52 (US 52) in West Kankakee north to US 41 in Skokie. In Chicago and the suburbs it's known as Cicero Avenue. Before this, Cicero Avenue was previously known as 48th Avenue, owing to its City of Chicago address of 4800 West.