U.S. Highway 14 in the state of Wisconsin runs northwest–southeast across the western to southwest portions of the state. It links La Crosse and the southwestern portion of the state with Madison and
The La Crosse West Channel Bridge carrying US 14, US 61, MN 16, and WIS 16 across the Mississippi River between La Crescent, Minnesota, and La Crosse, Wisconsin. This is the river's West Channel.