U.S. Highway 17 (US 17) in the U.S. state of North Carolina is a north–south highway that is known as the Coastal Highway in the southeastern half of the state and the Ocean Highway in other areas. The route enters the state from South Carolina near Calabash and leaves in the vicinity of the Great Dismal Swamp National Wildlife Refuge in Virginia. Between the US 64 freeway and the Virginia state line, US 17 is a four-lane divided highway with speed limits varying between 45 mph (72 km/h) and 70 mph (110 km/h).

Calabash is a small fishing town in Brunswick County, North Carolina, United States. As of the 2020 census, the population of the town was 2,011. It is known as the "Seafood Capital of the World" because of the town's seafood restaurants.